Results 121 to 130 of about 54,399,869 (294)

Summary of Research 1995, Department of Operations Research [PDF]

open access: yes, 1995
The views expressed in this report are those of the authors and do not reflect the official policy or position of the Department of Defense or the U.S.
Faculty of the Department of Operations Research, Naval Postgraduate School
core   +1 more source

Celebrating 10 years of the Irish Health Research Forum 2014-2024 [PDF]

open access: yes
This is a brief overview of the success of the Irish Health Research Forum over 10 years since its foundation in ...
Health Research Charities Ireland
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Blending Words & Numbers: Towards a Framework for Combining Quantitative and Qualitative Strategies for Organizational Research [PDF]

open access: yes
Blending qualitative and quantitative research methods is widely propagatedas a strategy for both quality control and enrichment of organizationresearch. This has been recognized in the organization literature for morethan twenty years.
Hertog,Friso,den
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

On the necessity for a third generation in mixed method design, theory, and research: overcoming the burden of the incompatibility thesis between qualitative and quantitative research [PDF]

open access: yesPedagogická Orientace, 2011
In this paper I strive for overcoming the burden of the incompatibility thesisbetween qualitative and quantitative research a I call for a third generation in mixedmethod design, theory, and research.
Manfred Max Bergman
doaj  

Biobanking in Ireland: Moving Forward. Irish Health Research Forum Recommendations and Event Report [PDF]

open access: yes
This report presents the proceedings of the Irish Health Research Forum on November 16th 2023, focusing on progressing biobanking in Ireland, and makes key recommendations for moving biobanking forward.Roche Products ...
Health Research Charities Ireland
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Interdependence of qualitative and quantitative factors in the dynamics of English verb paradigm

open access: yesPolylinguality and Transcultural Practices, 2014
The manuscript considers dynamics of English verb paradigm in diachronic aspect from system linguistics perspective. Corpus study of regular and irregular verbs is conducted, the mechanism of transition of verbs from irregular category to regular ...
M A Rudneva
doaj  

Health research in action 2021

open access: yes, 2021
Annual report for the HRB, which funds and performs research in ...
Health Research Board
core  

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