Results 101 to 110 of about 1,121,015 (394)

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1926-1940, December 2022., 2022
Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh   +5 more
wiley   +1 more source

Lifetime ostracism experiences and mechanisms of pain

open access: yesFrontiers in Pain Research, 2022
One social mechanism by which marginalization is enacted is via ostracism. Recent research has demonstrated ostracism's impact on physical health, but little is known about the relationship between accumulated lifetime experiences of ostracism and pain ...
Kaitlyn T. Walsh   +7 more
doaj   +1 more source

Exploring the Sensory Spaces of English Perceptual Verbs in Natural Language Data [PDF]

open access: yesCEUR-WS.org 2021, 2021
In this study, we explore how language captures the meaning of words, in particular meaning related to sensory experiences learned from statistical distributions across texts. We focus on the most frequent perception verbs of English analyzed from an and Agentive vs. Experiential distinction across the five basic sensory modalities: Visual (to look vs.
arxiv  

Temporal processing and context dependency in C. elegans mechanosensation [PDF]

open access: yeseLife 2018;7:e36419, 2018
A quantitative understanding of how sensory signals are transformed into motor outputs places useful constraints on brain function and helps reveal the brain's underlying computations. We investigate how the nematode C. elegans responds to time-varying mechanosensory signals using a high-throughput optogenetic assay and automated behavior ...
arxiv   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Communication shapes sensory response in multicellular networks [PDF]

open access: yes, 2015
Collective sensing by interacting cells is observed in a variety of biological systems, and yet a quantitative understanding of how sensory information is collectively encoded is lacking. Here we investigate the ATP-induced calcium dynamics of monolayers of fibroblast cells that communicate via gap junctions.
arxiv   +1 more source

Identifying Important Sensory Feedback for Learning Locomotion Skills [PDF]

open access: yesarXiv, 2023
Robot motor skills can be learned through deep reinforcement learning (DRL) by neural networks as state-action mappings. While the selection of state observations is crucial, there has been a lack of quantitative analysis to date. Here, we present a systematic saliency analysis that quantitatively evaluates the relative importance of different feedback
arxiv  

Quantitative Sensory Testing: QST

open access: yes, 2017
Quantitative Sensory Testing is a psychophysical method used to quantify the functional status of the somatosensory system. QST evaluates all types of afferent nerve fibers by applying quantitative and graded stimuli (graded von Frey hairs, several pinprick stimuli, pressure algometer, quantitative thermotesting, tuning fork etc) using specific testing
Sivan Schipper, Konrad Maurer
openaire   +2 more sources

Quantitative Sensory Testing in Spinal Cord Stimulation:A Narrative Review [PDF]

open access: yes
Objectives: Quantitative sensory testing (QST) has been used for decades to study sensory abnormalities in multiple conditions in which the somatosensory system is compromised, including pain.
Huygen, Frank J.P.M.   +3 more
core   +1 more source

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