Results 121 to 130 of about 1,121,015 (394)

Sensory Polymorphism and Behavior: When Machine Vision Meets Monkey Eyes [PDF]

arXiv, 2015
Polymorphism in the peripheral sensory system (e.g., congenital individual differences in photopigment configuration) is important in diverse research fields, ranging from evolutionary biology to engineering, because of its potential relationship to the cognitive and behavioral variability among individuals.
arxiv  

Future directions for the management of pain in osteoarthritis. [PDF]

, 2014
Osteoarthritis (OA) is the predominant form of arthritis worldwide, resulting in a high degree of functional impairment and reduced quality of life owing to chronic pain. To date, there are no treatments that are known to modify disease progression of OA
Aigner T, Anasuya Kuttapitiya, Balanescu AR, Bannuru RR, Chou R, da Costa BR, Danielsson L, Fanelli A, Fransen M, Haviv B, Huskisson EC, Lim YZ, Mankin HJ, McAlindon TE, Merlotti D, Nguyen US, Nidhi Sofat, Pelletier JP, Sagar DR, Sellers RS, Sofat N, Tannenbaum H, Wajed J, Wakitani S   +23 more
core   +1 more source

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

Molecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa, Zdenka Herudkova, Jan Hyl, Jakub Vlazny, Filip Sokol, Kvetoslava Matulova, Adam Folta, Jakub Hynst, Lucy Vojtova, Leos Kren, Martin Repko, Zdenek Racil, Jiri Mayer, Martin Culen   +13 more
wiley   +1 more source

Thermal and mechanical quantitative sensory testing values among healthy African American adults

Journal of Pain Research, 2019
Keesha L Powell-Roach,1 Yingwei Yao,2 Julienne N Rutherford,3 Judith M Schlaeger,3 Crystal L Patil,3 Marie L Suarez,4 David Shuey,4 Veronica Angulo,4 Jesus Carrasco,4 Miriam O Ezenwa,2 Roger B Fillingim,1 Zaijie J Wang,5 Robert E Molokie,5–7 Diana ...
Powell-Roach KL, Yao Y, Rutherford JN, Schlaeger JM, Patil CL, Suarez ML, Shuey D, Angulo V, Carrasco J, Ezenwa MO, Fillingim RB, Wang ZJ, Molokie RE, Wilkie DJ   +13 more
doaj  

Sensory bedside testing: a simple stratification approach for sensory phenotyping

PAIN Reports, 2020
. Introduction:. Stratification of patients according to the individual sensory phenotype has been suggested a promising method to identify responders for pain treatment.
Maren Reimer, Julia Forstenpointner, Alina Hartmann, Jan Carl Otto, Jan Vollert, Janne Gierthmühlen, Thomas Klein, Philipp Hüllemann, Ralf Baron   +8 more
doaj   +1 more source

Information Benchmark for Biological Sensors Beyond Steady States -- Mpemba-like sensory withdrawal effect [PDF]

Biological sensors rely on the temporal dynamics of ligand concentration for signaling. The sensory performance is bounded by the distinguishability between the sensory state transition dynamics under different environmental protocols. This work presents a comprehensive theory to characterize arbitrary transient sensory dynamics of biological sensors ...
arxiv   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

Molecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu, Fenglin Shen, Yang Liu, Ziqing Zhong, Yongling Chen, Zhiyuan Xia, Cuiju Mo, Hongxiu Yu   +7 more
wiley   +1 more source

Quantitative sensory testing in physically active individuals and patients who underwent multidisciplinary pain therapy in the longitudinal course

Journal of Pain Research, 2018
Ulrike Dapunt, Simone Gantz, Anastasiya Zhuk, Katharina Gather, Haili Wang, Marcus Schiltenwolf Center for Orthopaedics, Trauma Surgery and Spinal Cord Injury, Heidelberg University Hospital, Schlierbacher Landstrasse, Heidelberg, Germany Objective: The ...
Dapunt U, Gantz S, Zhuk A, Gather K, Wang H, Schiltenwolf M   +5 more
doaj  

Hypoxia-inducible factor 1a protects peripheral sensory neurons from diabetic peripheral neuropathy by suppressing accumulation of reactive oxygen species [PDF]

arXiv, 2018
Diabetic peripheral neuropathy (DPN) is one of the most common diabetic complications. Mechanisms underlying nerve damage and sensory loss following metabolic dysfunction remain large unclear. Recently, hyperglycemia-induced mitochondrial dysfunction and the generation of ROS have gained attention as possible mechanisms of organ damage in diabetes ...
arxiv  

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source