Results 131 to 140 of about 284,024 (323)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

open access: yesFEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Lack of evidence for central sensitization in idiopathic, non-traumatic neck pain : a systematic review [PDF]

open access: yes, 2015
Background: Chronic neck pain is a common problem with a poorly understood pathophysiology. Often no underlying structural pathology can be found and radiological imaging findings are more related to age than to a patient's symptoms.
Bramer, Wichor   +9 more
core   +1 more source

Quantitative sensory testing of periauricular skin in healthy adults [PDF]

open access: gold, 2020
Wen Lin   +6 more
openalex   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

REPEATABILITY AND RELIABILITY OF A NEW THERMOTACTILE QUANTITATIVE SENSORY TESTING ALGORITHM

open access: yesZdravniški Vestnik, 2009
Background Thermotactile quantitative sensory testing (TQST), as a part of quantitative sensory testing (QST), has been used for quantifying perceived thermal sensory thresholds.
Maruša Klopčič, Miroljub Jakovljević
doaj  

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

Methods in Psychological Research [PDF]

open access: yes, 2002
Psychologists collect empirical data with various methods for different reasons. These diverse methods have their strengths as well as weaknesses. Nonetheless, it is possible to rank them in terms of different critieria.
Chow, Siu L.
core  

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