Results 191 to 200 of about 322,559 (240)

Quantitative structure–activity relationship study on antitumour activity of a series of flavonoids

, 2011
Weixuan Wang, Hongzong Si, Ziding Zhang
openalex   +2 more sources

Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury

Advanced Functional Materials, EarlyView.
After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen, Yvonne Shen, Yutong Shao, Tenghuan Ge, Haowen Qiao, Shangzhou Xia, Yafei Qu, Yuanpu Chiu, Ying Qin, Zhen Zhao   +9 more
wiley   +1 more source

Quantitative structure-activity relationship and ADME prediction studies on series of spirooxindoles derivatives for anti-cancer activity against colon cancer cell line HCT-116. [PDF]

Heliyon
Kaur S, Kaur J, Zarger BA, Islam N, Mir N.   +4 more
europepmc   +1 more source

Probing Early Particle‐Cell Membrane Interactions via Single‐Cell and Single‐Particle Interaction Analysis

Advanced Functional Materials, EarlyView.
The pre‐internalization phase of endocytosis remains poorly characterized at single‐cell levels. Single‐cell pre‐internalization mechanics are investigated using advanced robotic techniques. Cancer cells exhibit biphasic adhesion – rapid initial binding followed by reinforcement – while fibroblasts show gradual engagement.
Houari Bettahar, Christos Tapeinos, Oğulcan Işıtman, Carmine D'Amico, Alexandra Correia, Hélder A. Santos, Quan Zhou   +6 more
wiley   +1 more source

Identification of the single and combined acute toxicity of Cr and Ni with Heterocypris sp. and the quantitative structure-activity relationship (QSAR) model. [PDF]

PLoS One
Su C, Hua Y, Liu Y, Tao S, Jia F, Zhao W, Lin W.   +6 more
europepmc   +1 more source

The Composition of Triterpene Glycosides in the Sea Cucumber Psolus peronii: Anticancer Activity of the Glycosides against Three Human Breast Cancer Cell Lines and Quantitative Structure–Activity Relationships (QSAR) [PDF]

Alexandra S. Silchenko, Anatoly I. Kalinovsky, Sergey A. Avilov, Roman S. Popov, Ekaterina A. Chingizova, Ekaterina S. Menchinskaya, Elena Zelepuga, Kseniya M. Tabakmakher, Vadim Georgievich Stepanov, Vladimir I. Kalinin   +9 more
openalex   +1 more source

A Robust Dual‐mode Self‐Monitoring Battery Thermal Management System via Bilayer Structural Design

Advanced Functional Materials, EarlyView.
An adaptive dual‐mode material capable of both evaporative cooling and photothermal preheating is developed. It achieves a cooling efficiency of 53.9%, surpassing existing evaporative cooling counterparts, and a self‐monitoring capability, making it ideal for electric vehicles, portable electronics, and grid‐scale energy storage.
Shanchi Wang, Zhihao Huang, Zhiguang Xu, Fang Guo, Tao Zhang, Min Hong, Pingan Song, Yan Zhao   +7 more
wiley   +1 more source

Quantitative structure-activity relationship of 2,6-dimethoxy-N-(3-(4-substituted phenyl)isoxazol-5-yl)benzamide for the inhibition of chitin synthesis. [PDF]

J Pestic Sci
Mori K, Miyashita M, Mori S, Shibata N, Nakagawa Y.   +4 more
europepmc   +1 more source

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source