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Cortical Iron Accumulation as an Imaging Marker for Neurodegeneration in Clinical Cognitive Impairment Spectrum: A Quantitative Susceptibility Mapping Study

Korean Journal of Radiology, 2023
Objective Cortical iron deposition has recently been shown to occur in Alzheimer’s disease (AD). In this study, we aimed to evaluate how cortical gray matter iron, measured using quantitative susceptibility mapping (QSM), differs in the clinical ...
H. Kim   +5 more
semanticscholar   +1 more source

Inverse Problem in Quantitative Susceptibility Mapping

SIAM Journal on Imaging Sciences, 2014
Summary: Quantitative susceptibility mapping (QSM) is a new medical imaging technique that can visualize magnetic susceptibility, changes of which in tissue indicate various disease processes involving iron transport. The inverse problem of QSM is to recover the susceptibility distribution of the human body from the measured local field that is ...
Jae Kyu Choi   +4 more
openaire   +2 more sources

Quantitative Susceptibility Mapping: Basic Methods and Clinical Applications.

Radiographics, 2022
Quantitative susceptibility mapping (QSM), one of the advanced MRI techniques for evaluating magnetic susceptibility, offers precise quantitative measurements of spatial distributions of magnetic susceptibility.
T. Harada   +9 more
semanticscholar   +1 more source

The Current State of Susceptibility-Weighted Imaging and Quantitative Susceptibility Mapping in Head Trauma.

Neuroimaging clinics of North America, 2023
Susceptibility-weighted imaging (SWI) is a MR imaging technique suited to detect structural and microstructural abnormalities in traumatic brain injury (TBI).
C. Hsu, S. Sethi, E. Haacke
semanticscholar   +1 more source

Altered brain iron depositions from aging to Parkinson's disease and Alzheimer's disease: A quantitative susceptibility mapping study

NeuroImage, 2022
Brain iron deposition is a promising marker for human brain health, providing insightful information for understanding aging as well as neurodegenerations, e.g., Parkinson's disease (PD) and Alzheimer's disease (AD).
Xiaojun Guan   +23 more
semanticscholar   +1 more source

Quantitative Susceptibility Mapping: Concepts and Applications

Clinical Neuroradiology, 2015
To review the fundamental principles of susceptibility-weighted imaging (SWI) and quantitative susceptibility mapping (QSM), and to discuss recent clinical developments.SWI is a magnetic resonance imaging method that takes advantage of magnitude signal loss and phase information to reveal anatomic and physiologic information about tissue and venous ...
J R, Reichenbach   +3 more
openaire   +2 more sources

Diffusion tensor image analysis along the perivascular space and quantitative susceptibility mapping in the diagnosis and severity assessment of Parkinson’s disease

Quantitative Imaging in Medicine and Surgery
Background Increased iron accumulation measured by quantitative susceptibility mapping (QSM) has been observed in various brain regions, especially substantia nigra (SN), in Parkinson’s disease (PD).
Chen-Xi Ni   +9 more
semanticscholar   +1 more source

Image Reconstruction in Quantitative Susceptibility Mapping

SIAM Journal on Imaging Sciences, 2016
Summary: This paper deals with a reconstruction problem in magnetic resonance imaging where the Fourier transform of the sought-for object can't be obtained in the vicinity of a cone-shaped surface. This leads to streak-shaped artifacts in the sagittal views of the object.
openaire   +2 more sources

Unsupervised resolution-agnostic quantitative susceptibility mapping using adaptive instance normalization

Medical Image Anal., 2022
Quantitative susceptibility mapping (QSM) is a useful magnetic resonance imaging (MRI) technique that provides the spatial distribution of magnetic susceptibility values of tissues. QSMs can be obtained by deconvolving the dipole kernel from phase images,
Gyutaek Oh   +5 more
semanticscholar   +1 more source

Depth- and curvature-based quantitative susceptibility mapping analyses of cortical iron in Alzheimer's disease.

Cerebral Cortex
In addition to amyloid beta plaques and neurofibrillary tangles, Alzheimer's disease (AD) has been associated with elevated iron in deep gray matter nuclei using quantitative susceptibility mapping (QSM).
J. Merenstein   +6 more
semanticscholar   +1 more source

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