Results 121 to 130 of about 282,753 (347)

Expression quantitative trait loci analysis identifies associations between genotype and gene expression in human intestine.

Gastroenterology, 2013
BACKGROUND & AIMS Genome-wide association studies have greatly increased our understanding of intestinal disease. However, little is known about how genetic variations result in phenotypic changes.
B. Kabakchiev, M. Silverberg
semanticscholar   +1 more source

Genomic Evaluation of Recombination in Small Highly Inbred Beef Cattle Populations

Animal Research and One Health, EarlyView.
The study characterizes recombination in small beef cattle populations, revealing higher rates in CGC composites compared to inbred Line 1 Herefords. It identifies significant SNP associations linked to recombination across various autosomes, highlighting complex polygenic influences, with implications for genetic diversity and breeding strategies ...
E. Hay, A. S. Ling
wiley   +1 more source

Identification of late blight resistance quantitative trait loci in Solanum pimpinellifolium accession PI 270441

The Plant Genome, Volume 15, Issue 4, December 2022., 2022
Abstract Late blight (LB), caused by the oomycete Phytophthora infestans, is one of the most destructive diseases of the cultivated tomato (Solanum lycopersicum L.) and potato (Solanum tuberosum L.) worldwide. Genetic changes in the pathogen have resulted in the emergence of new genotypes, overcoming formerly effective fungicides or host resistance ...
Matthew T. Sullenberger, Mengyuan Jia, Sihui Gao, Hamid Ashrafi, Majid R. Foolad   +4 more
wiley   +1 more source

Dissection of the E8 locus in two early maturing Canadian soybean populations

Frontiers in Plant Science
Soybean [Glycine max (L.) Merr.] is a short-day crop for which breeders want to expand the cultivation range to more northern agro-environments by introgressing alleles involved in early reproductive traits.
Jérôme Gélinas Bélanger, Jérôme Gélinas Bélanger, Tanya Rose Copley, Valerio Hoyos-Villegas, Louise O’Donoughue   +4 more
doaj   +1 more source

Joint tests for quantitative trait loci in experimental crosses

Genetics Selection Evolution, 2004
Selective genotyping is common because it can increase the expected correlation between QTL genotype and phenotype and thus increase the statistical power of linkage tests (i.e., regression-based tests).
Xu Shizhong, Amos Christopher I, Travis Elizabeth L, Bullard Daniel C, Yi Nengjun, Yang Dongyan, Beasley T Mark, Allison David B   +7 more
doaj   +1 more source

Quantitative trait loci of stripe rust resistance in wheat

Theoretical and Applied Genetics, 2013
Key messageOver 140 QTLs for resistance to stripe rust in wheat have been published and through mapping flanking markers on consensus maps, 49 chromosomal regions are identified.AbstractOver thirty publications during the last 10 years have identified ...
G. Rosewarne, S. Herrera-Foessel, R. Singh, J. Huerta-Espino, C. Lan, Zhonghu He   +5 more
semanticscholar   +1 more source

Mapping and validation of major and stable QTL for flag leaf size from tetraploid wheat

The Plant Genome, Volume 15, Issue 4, December 2022., 2022
Abstract The flag leaf is an important photosynthetic organ of wheat (Triticum aestivum L.). Appropriate flag leaf size can effectively increase grain yield. In this study, a tetraploid wheat population of recombinant inbred lines (RILs) and a genetic map constructed based on a wheat 55K single‐nucleotide polymorphism (SNP) array were used to identify ...
Jian Wang, Hang Liu, Conghao Zhao, Huaping Tang, Yang Mu, Qiang Xu, Mei Deng, Qiantao Jiang, Guoyue Chen, Pengfei Qi, Jirui Wang, Yunfeng Jiang, Shisheng Chen, Yuming Wei, Youliang Zheng, Xiujin Lan, Jian Ma   +16 more
wiley   +1 more source

Massively parallel reporter assay confirms regulatory potential of hQTLs and reveals important variants in lupus and other autoimmune diseases

HGG Advances
Summary: We designed a massively parallel reporter assay (MPRA) in an Epstein-Barr virus transformed B cell line to directly characterize the potential for histone post-translational modifications, i.e., histone quantitative trait loci (hQTLs ...
Yao Fu, Jennifer A. Kelly, Jaanam Gopalakrishnan, Richard C. Pelikan, Kandice L. Tessneer, Satish Pasula, Kiely Grundahl, David A. Murphy, Patrick M. Gaffney   +8 more
doaj  

Integrative Bioinformatics Approaches for Identification of Drug Targets in Hypertension

Frontiers in Cardiovascular Medicine, 2018
High blood pressure or hypertension is an established risk factor for a myriad of cardiovascular diseases. Genome-wide association studies have successfully found over nine hundred loci that contribute to blood pressure.
Daiane Hemerich, Daiane Hemerich, Jessica van Setten, Vinicius Tragante, Folkert W. Asselbergs, Folkert W. Asselbergs, Folkert W. Asselbergs, Folkert W. Asselbergs   +7 more
doaj   +1 more source

STATISTICAL THRESHOLD VALUES FOR LOCATING QUANTITATIVE TRAIT LOCI [PDF]

, 1998
The detection and location of quantitative trait loci (QTL) that control quantitative characters is a problem of great interest to the genetic mapping community.
Doerge, R. W.
core   +2 more sources