Results 211 to 220 of about 313,777 (344)

Genetic Mapping of Orofacial Traits Reveals a Single Genomic Region Associated With Differences in Multiple Parameters of Jaw Size Between Astyanax mexicanus Surface and Cavefish

open access: yesEvolution &Development, EarlyView.
By performing a genetic association study in cave × surface fish F2 hybrids, we discovered that premaxilla width, dentary length, and maxillary length are all significantly associated with a region on Chromosome 13 containing 109 genes. ABSTRACT The regulation of bone size is a poorly understood and complex developmental process.
Amanda K. Powers   +7 more
wiley   +1 more source

Identification of methylation quantitative trait loci (mQTLs) influencing promoter DNA methylation of alcohol dependence risk genes

open access: green, 2014
Huiping Zhang   +7 more
openalex   +1 more source

Genetic risk factor identification for common epilepsies guided by integrative omics data analysis

open access: yesEpilepsia, EarlyView.
Abstract Objective Genetic generalized epilepsies (GGEs) comprise the most common genetically determined epilepsy syndromes, following a complex mode of inheritance. Although many important common and rare genetic factors causing or contributing to these epilepsies have been identified in the past decades, many features of the genetic architecture are ...
Ashwini Mushunuri   +9 more
wiley   +1 more source

Meta‐analysis of genetic mapping studies in mice reveals candidate epilepsy modifier genes that are outside the current drug development landscape

open access: yesEpilepsia, EarlyView.
Abstract Objective Despite decades of development in anti‐seizure medications, ~30% of individuals remain refractory to all treatments, and none of the existing therapies are disease modifying. Identifying targets outside the current preclinical paradigm is critically important.
Giovanna L. Durante   +4 more
wiley   +1 more source

Mapping Multiple Quantitative Trait Loci by Bayesian Classification

open access: green, 2004
Min Zhang   +4 more
openalex   +1 more source

Multiple Interval Mapping for Quantitative Trait Loci [PDF]

open access: bronze, 1999
Chen-Hung Kao   +2 more
openalex   +1 more source

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