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Quantitative Trait Loci (QTL) Mapping
2019Quantitative trait loci (QTL) are genetic regions that influence phenotypic variation of a complex trait, often through genetic interactions with each other and the environment. These are commonly identified through a statistical genetic analysis known as QTL mapping. Here, I present a step-by-step, practical approach to QTL mapping along with a sample
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Mapping quantitative trait loci for traits defined as ratios
Genetica, 2007Many traits are defined as ratios of two quantitative traits. Methods of QTL mapping for regular quantitative traits are not optimal when applied to ratios due to lack of normality for traits defined as ratios. We develop a new method of QTL mapping for traits defined as ratios.
Runqing, Yang, Jiahan, Li, Shizhong, Xu
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Interaction and quantitative trait loci
Australian Journal of Experimental Agriculture, 2004Parallel searches for quantitative trait loci (QTL) for growth-related traits in different populations frequently detect sets of QTL that hardly overlap. Thus, many QTL potentially exist. Tools for the detection of QTL that interact are available and are currently being tested. Initial results suggest that epistasis is widespread.
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Mapping of Quantitative Trait Loci
2015The genomic region associated with the expression of a quantitative trait is referred to as quantitative trait locus (QTL), which may contain one or more genes. QTLs have been grouped into different categories on the basis of their effect size, the effect of environment on their expression, and the manner of their action. QTL mapping is generally based
B. D. Singh, A. K. Singh
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Finding Quantitative Trait Loci Genes
2011The goal of quantitative trait loci (QTL) mapping is to identify genes underlying an observed trait in the genome using genetic markers. In experimental organisms, the QTL mapping experiment usually involves crossing two inbred lines with substantial differences in a trait, and then scoring the trait in the segregating progeny.
Hui Wang +2 more
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Quantitative Trait Loci Mapping.
Alcohol health and research worldResearchers interested in the physical locations of genes that influence a person's alcohol-related behaviors can use a method known as quantitative trait loci (QTL) mapping to identify the approximate locations of genes in the genome. QTL mapping can use recombinant inbred mouse strains, which are sets of inbred strains derived from cross-breeding the
Judith E, Grisel, John C, Crabbe
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Mapping Expression Quantitative Trait Loci
2012The transcript abundance can be treated as a classical quantitative trait, and thus, mapping can be done on the transcript (Brem et al. 2002; Cheung and Spielman 2002; Schadt et al. 2003).Mendelian loci in the genome that control the expression levels of transcripts are called expression quantitative trait loci (eQTL).
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