Results 91 to 100 of about 246,153 (184)

Universality and predictability in molecular quantitative genetics [PDF]

arXiv, 2013
Molecular traits, such as gene expression levels or protein binding affinities, are increasingly accessible to quantitative measurement by modern high-throughput techniques. Such traits measure molecular functions and, from an evolutionary point of view, are important as targets of natural selection. We review recent developments in evolutionary theory
arxiv  

Four additional mouse crosses improve the lipid QTL landscape and identify Lipg as a QTL gene[S]

Journal of Lipid Research, 2009
To identify genes controlling plasma HDL and triglyceride levels, quantitative trait locus (QTL) analysis was performed in one backcross, (NZO/H1Lt × NON/LtJ) × NON/LtJ, and three intercrosses, C57BL/6J × DBA/2J, C57BL/6J × C3H/HeJ, and NZB/B1NJ × NZW ...
Zhiguang Su, Naoki Ishimori, Yaoyu Chen, Edward H. Leiter, Gary A. Churchill, Beverly Paigen, Ioannis M. Stylianou   +6 more
doaj  

Inferring genotype-phenotype maps using attention models [PDF]

arXiv
Predicting phenotype from genotype is a central challenge in genetics. Traditional approaches in quantitative genetics typically analyze this problem using methods based on linear regression. These methods generally assume that the genetic architecture of complex traits can be parameterized in terms of an additive model, where the effects of loci are ...
arxiv  

Hd1, a Major Photoperiod Sensitivity Quantitative Trait Locus in Rice, Is Closely Related to the Arabidopsis Flowering Time Gene CONSTANS

The Plant Cell, 2000
M. Yano, Y. Katayose, M. Ashikari, U. Yamanouchi, L. Monna, T. Fuse, T. Baba, Kimiko Yamamoto, Y. Umehara, Y. Nagamura, Takuji Sasaki   +10 more
semanticscholar   +1 more source

Expression Quantitative Trait Locus

Definitions, 2020

semanticscholar   +1 more source

Expression Quantitative Trait Locus of Wood Formation-Related Genes in Salix suchowensis. [PDF]

Int J Mol Sci, 2023
Chen L, Liu L, Yang G, Li X, Dai X, Xue L, Yin T.   +6 more
europepmc   +1 more source

StarBASE-GP: Biologically-Guided Automated Machine Learning for Genotype-to-Phenotype Association Analysis [PDF]

arXiv
We present the Star-Based Automated Single-locus and Epistasis analysis tool - Genetic Programming (StarBASE-GP), an automated framework for discovering meaningful genetic variants associated with phenotypic variation in large-scale genomic datasets. StarBASE-GP uses a genetic programming-based multi-objective optimization strategy to evolve machine ...
arxiv  

QTL IciMapping: Integrated software for genetic linkage map construction and quantitative trait locus mapping in biparental populations

, 2015
L. Meng, Huihui Li, Luyan Zhang, Jiankang Wang   +3 more
semanticscholar   +1 more source

Statistical power in genome-wide association studies and quantitative trait locus mapping

Heredity, 2019
Meiyue Wang, Shizhong Xu
semanticscholar   +1 more source

Placental expression quantitative trait loci in an East Asian population

HGG Advances
Summary: Expression quantitative trait loci (eQTL) analysis measures the contribution of genetic variation in gene expression on complex traits. Although this methodology has been used to examine gene regulation in numerous human tissues, eQTL research ...
Jaeyong Choi, Seung Mi Lee, Errol R. Norwitz, Ji Hoi Kim, Young Mi Jung, Chan-Wook Park, Jong Kwan Jun, Dakyung Lee, Yongjoon Jin, Sookyung Kim, Bukyoung Cha, Joong Shin Park, Jong-Il Kim   +12 more
doaj