Results 111 to 120 of about 361,741 (406)

Map-based quantitative trait locus identification

Poultry Science, 1997
Poultry gene mappers chose microsatellites as the main source of genetic markers for poultry genome mapping, similar to the marker type used for other farm animals, laboratory animals, and humans. Optimal strategies for applying DNA markers in poultry populations are discussed, including the number of markers to be used, genome representation ...
openaire   +3 more sources

A quantitative trait locus for nictation behavior on chromosome V

microPublication biology, 2017
Lee et al., 2017 showed that CB4856 has a lower nictation ratio (the number of nictating dauers over the number of moving dauers on a micro-dirt chip) than N2, and that a genetic locus (nict-1) on chromosome IV mediates this phenotype difference. Although this paper had no evidence of any other genetic loci for nictation behavior, we have studied other
Daehan Lee, Jun Kim, Junho Lee
openaire   +3 more sources

Advances in Electrical Materials for Bone and Cartilage Regeneration: Developments, Challenges, and Perspectives

Advanced Science, EarlyView.
This review explores the challenges of treating bone and cartilage defects, emphasizing the role of endogenous electric fields in bone and cartilage regeneration. It highlights recent advancements in electroactive biomaterials, including nanogenerators, piezoelectric materials, triboelectric scaffold, and zwitterionic hydrogels.
Yubin Yao, Xi Cui, Shenglong Ding, Ketao Wang, Mingzhu Zhang   +4 more
wiley   +1 more source

Novel Resampling Improves Statistical Power for Multiple-Trait QTL Mapping

G3: Genes, Genomes, Genetics, 2017
Multiple-trait analysis typically employs models that associate a quantitative trait locus (QTL) with all of the traits. As a result, statistical power for QTL detection may not be optimal if the QTL contributes to the phenotypic variation in only a ...
Riyan Cheng, R. W. Doerge, Justin Borevitz   +2 more
doaj   +1 more source

Accurate Estimation of Quantitative Trait Locus Effects with Epistatic by Improved Variational Linear Regression [PDF]

arXiv, 2015
Bayesian approaches to variable selection have been widely used for quantitative trait locus (QTL) mapping. The Markov chain Monte Carlo (MCMC) algorithms for that aim are often difficult to be implemented for high-dimensional variable selection problems, such as the ones arising in epistatic analysis.
arxiv  

Alnustone Ameliorates Metabolic Dysfunction‐Associated Steatotic Liver Disease by Facilitating Mitochondrial Fatty Acid β‐Oxidation via Targeting Calmodulin

Advanced Science, EarlyView.
This study identifies alnustone, a natural compound from Alpinia katsumadai, as a potent therapeutic agent for MASLD and MASH. Alnustone enhances mitochondrial fatty acid β‐oxidation by directly targeting calmodulin, improving liver steatosis, fibrosis, and insulin resistance in vivo.
Shourui Hu, Xiaofan Liang, Yiming Qin, Yuxuan Li, Yue Liu, Congcong Liu, Zongxuan Lin, Chunxuan Geng, Yanqi Xu, Daimin Wei, Yingying Qin, Han Zhao, Yuqing Zhang, Zi‐Jiang Chen   +13 more
wiley   +1 more source

forqs: Forward-in-time Simulation of Recombination, Quantitative Traits, and Selection [PDF]

, 2013
forqs is a forward-in-time simulation of recombination, quantitative traits, and selection. It was designed to investigate haplotype patterns resulting from scenarios where substantial evolutionary change has taken place in a small number of generations ...
Kessner, Darren, Novembre, John
core  

Integrating Dense Genotyping with High‐Throughput Phenotyping Empowers the Genetic Dissection of Berry Quality and Resilience Traits in Grapevine

Advanced Science, EarlyView.
Researchers develop advanced tools to study grapevine traits like berry quality and stress resilience. A 200K SNP array and high‐throughput phenotyping enable the identification of loci linked to berry shape, sugar content, acidity, and cold tolerance. Functional validation of genes such as NAC08 reveals roles in cold tolerance.
Yuyu Zhang, Yongjian Wang, Michael Henke, Pablo Carbonell‐Bejerano, Zemin Wang, Pierre‐François Bert, Yi Wang, Huayang Li, Junhua Kong, Peige Fan, Zhanwu Dai, Zhenchang Liang   +11 more
wiley   +1 more source

Gene by environment QTL mapping through multiple trait analyses in blood pressure salt-sensitivity: identification of a novel QTL in rat chromosome 5

BMC Medical Genetics, 2006
Background The genetic mechanisms underlying interindividual blood pressure variation reflect the complex interplay of both genetic and environmental variables.
Tôrres César H, Pereira Alexandre C, Soler Júlia, Krieger José E   +3 more
doaj   +1 more source

Accounting for genetic interactions improves modeling of individual quantitative trait phenotypes in yeast. [PDF]

, 2016
Experiments in model organisms report abundant genetic interactions underlying biologically important traits, whereas quantitative genetics theory predicts, and data support, the notion that most genetic variance in populations is additive.
Bloom, Joshua S, Carlborg, Örjan, Forsberg, Simon KG, Kruglyak, Leonid, Sadhu, Meru J   +4 more
core   +3 more sources