Results 161 to 170 of about 361,741 (406)
Advanced Science, EarlyView.This work proposes the first perovskite/graphene heterostructure‐based FET biosensor with uniquely biotunable ternary logic gating functionality for the detection of human IL6 cytokines. The biosensor integrates a lateral perovskite‐on‐graphene heterostructure phototransistor with a vertical bio‐nano‐photonic filter, achieving ultrahigh sensitivity ...
Jiaxing Sun +7 more
wiley +1 more source
A Pattern Discovery-Based Method for Detecting Multi-Locus Genetic Association [PDF]
arXiv, 2007 Methods to effectively detect multi-locus genetic association are becoming increasingly relevant in the genetic dissection of complex trait in humans. Current approaches typically consider a limited number of hypotheses, most of which are related to the effect of a single locus or of a relatively small number of neighboring loci on a chromosomal region.
arxiv
A Latent Variable Approach to Multivariate Quantitative Trait Loci [PDF]
, 2010 A novel approach based on latent variable modelling is presented for the analysis of multivariate quantitative and qualitative trait loci. The approach is general in the sense that it enables the joint analysis of many kinds of quantitative and ...
Bob O' +3 more
core +1 more source
Advanced Science, EarlyView.DeepTFBS leverages deep learning to predict transcription factor binding sites across species, integrating multi‐task and transfer learning approaches to improve performance in data‐scarce scenarios. This study demonstrates enhanced accuracy in intra‐ and cross‐species prediction, revealing conserved regulatory patterns and functional variants.
Jingjing Zhai +8 more
wiley +1 more source
Mapping resistant QTLs for rice sheath blight disease with a doubled haploid population
Journal of Integrative Agriculture, 2015 Sheath blight (SB) disease, caused by Rhizoctonia solani Kühn, is one of the most serious diseases causing rice (Oryza sativa L.) yield loss worldwide. A doubled haploid (DH) population was constructed from a cross between a japonica variety CJ06 and an ...
Yu-xiang ZENG +6 more
doaj
Long and short range multi-locus QTL interactions in a complex trait of yeast [PDF]
arXiv, 2015 We analyse interactions of Quantitative Trait Loci (QTL) in heat selected yeast by comparing them to an unselected pool of random individuals. Here we re-examine data on individual F12 progeny selected for heat tolerance, which have been genotyped at 25 locations identified by sequencing a selected pool [Parts, L., Cubillos, F. A., Warringer, J., Jain,
arxiv
A new method for Quantitative Trait Loci Detection [PDF]
, 2010 We consider the likelihood ratio test (LRT) process related to the test of the absence of QTL on the interval $[0,T]$ representing a chromosome (a QTL denotes a quantitative trait locus, i.e. a gene with quantitative effect on a trait).
DELMAS, Céline, Rabier, Charles-Elie
core +1 more source
Rapid adaptation of a polygenic trait after a sudden environmental shift
, 2017 Although a number of studies have shown that natural and laboratory populations initially well-adapted to their environment can evolve rapidly when conditions suddenly change, the dynamics of rapid adaptation are not well understood.
Jain, Kavita, Stephan, Wolfgang
core +1 more source
Quantitative trait locus mapping of human blood pressure to a genetic region at or near the lipoprotein lipase gene locus on chromosome 8p22. [PDF]
, 1996 Da Wu +12 more
openalex +1 more source
Sequential Quantitative Trait Locus Mapping in Experimental Crosses
Statistical Applications in Genetics and Molecular Biology, 2007 The etiology of complex diseases is heterogeneous. The presence of risk alleles in one or more genetic loci affects the function of a variety of intermediate biological pathways, resulting in the overt expression of disease. Hence, there is an increasing focus on identifying the genetic basis of disease by systematically studying phenotypic traits ...
Satagopan, J M, Sen, S, Churchill, G A
openaire +3 more sources