High-dimensional covariance regression with application to co-expression QTL detection [PDF]
While covariance matrices have been widely studied in many scientific fields, relatively limited progress has been made on estimating conditional covariances that permits a large covariance matrix to vary with high-dimensional subject-level covariates.
arxiv
A rapid method for computing the inverse of the gametic covariance matrix between relatives for a marked Quantitative Trait Locus [PDF]
G. Abdel-Azim, A.E. Freeman
openalex +1 more source
Abstract Background Glioblastoma (GBM) is largely refractory to antibodies against programmed cell death 1 (anti‐PD‐1) therapy. Fully understanding the cellular heterogeneity and immune adaptations in response to anti‐PD‐1 therapy is necessary to design more effective immunotherapies for GBM.
Rongrong Zhao+11 more
wiley +1 more source
A convex formulation of covariate-adjusted Gaussian graphical models via natural parametrization [PDF]
Gaussian graphical models (GGMs) are widely used for recovering the conditional independence structure among random variables. Recently, several key advances have been made to exploit an additional set of variables for better estimating the GGMs of the variables of interest.
arxiv
Trans-ethnic fine mapping of a quantitative trait locus for circulating angiotensin I-converting enzyme (ACE) [PDF]
Colin A. McKenzie
openalex +1 more source
Abstract Background Hepatocellular carcinoma (HCC) is a deadly malignancy known for its ability to evade immune surveillance. NOP2/Sun RNA methyltransferase family member 2 (NSUN2), an RNA methyltransferase involved in carcinogenesis, has been associated with immune evasion and energy metabolism reprogramming.
Jinhua Jiang+6 more
wiley +1 more source
Quantitative trait locus mapping of osmotic stress response in the fungal wheat pathogen Zymoseptoria tritici. [PDF]
Stapley J, McDonald BA.
europepmc +1 more source
Analysis of Multiple Quantitative Trait Locus Using Genetic Algorithms and AIC.
Reiichiro Nakamichi+2 more
openalex +2 more sources
Quantitative Trait Locus Mapping of Loci Influencing Elongation Factor 1α Content in Maize Endosperm [PDF]
Xuelu Wang+3 more
openalex +1 more source
Inorganic Nanoparticles in Reproduction Biology: Opportunities and Challenges
The development of inorganic metal and metal oxide nanoparticles (MNPs) has attracted significant attention in biomedical and biotechnological fields. An emerging field in this context is the use of MNPs in reproduction biology. Here, we review the development of MNPs in the field of reproduction by focusing on their interactions with highly delicate ...
Stephan Barcikowski+3 more
wiley +1 more source