Results 281 to 290 of about 283,140 (381)

Repurposing Acebutolol for Osteoporosis Treatment: Insights From Multi‐Omics and Multi‐Modal Data Analysis

Clinical Pharmacology &Therapeutics, EarlyView.
Overview of a multi‐omics based drug repurposing strategy. The systematic drug repurposing strategy included the following steps: (1) osteoporosis driver signaling networks were identified from multi‐omics data; (2) drug functional modules were obtained using a network fusion approach to integrate drug similarity information; (3) all drugs were ranked ...
Dan‐Yang Liu, Hui Shen, Jonathan Greenbaum, Qiao‐Rong Yi, Shuang Liang, Yue Zhang, Jia‐Chen Liu, Chuan Qiu, Lan‐Juan Zhao, Qing Tian, Kuan‐Jui Su, Zhe Luo, Li Wu, Xiang‐He Meng, Hong‐Mei Xiao, Yun Deng, Yang Li, Dragana Lovre, Vivian Fonseca, Fernando L. Sanchez, Li‐Jun Tan, Hong‐Wen Deng   +21 more
wiley   +1 more source

Mapping of a Major-Effect Quantitative Trait Locus for Seed Dormancy in Wheat. [PDF]

Int J Mol Sci
Gao Y, Qiao L, Mei C, Nong L, Li Q, Zhang X, Li R, Gao W, Chen F, Chang L, Zhang S, Guo H, Cheng T, Wen H, Chang Z, Li X.   +15 more
europepmc   +1 more source

Genomic Analysis in the sting-2 Quantitative Trait Locus for Defensive Behavior in the Honey Bee, Apis mellifera [PDF]

, 2003
Neil F. Lobo
openalex   +1 more source

Investigating How Mandatory Sustainability Reporting Influences Corporate Governance Effects on ESG Performance: From Obligation to Impact for Sustainable Development

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Under the current global institutional endorsement for corporate sustainability, understanding if companies are effectively improving their ESG performance represents a key topic. Therefore, this research examines whether and how mandatory sustainability reporting affects companies' environmental and social performance. The study also explores
Gianluca Vitale, Sebastiano Cupertino, Giovanni Schiuma, Ciro Troise   +3 more
wiley   +1 more source

An isoform quantitative trait locus in SBNO2 links genetic susceptibility to Crohn's disease with defective antimicrobial activity. [PDF]

Nat Commun
Aschenbrenner D, Nassiri I, Venkateswaran S, Pandey S, Page M, Drowley L, Armstrong M, Kugathasan S, Fairfax B, Uhlig HH.   +9 more
europepmc   +1 more source

Quantitative trait locus detection in commercial broiler lines using candidate regions [PDF]

, 2003
Burt, D W, de Koning, D J, Griffin, H, Haley, C S, Hocking, P M, Law, A, Morris, A, Vincent, J, Windsor, D   +8 more
core  

The role of the PTHrP/Ihh feedback loop in the unusual growth plate location in mammalian metatarsals and pisiforms

Developmental Dynamics, EarlyView.
Abstract Background Longitudinal skeletal growth takes place in the cartilaginous growth plates. While growth plates are found at either end of conventional long bones, they occur at a variety of locations in the mammalian skeleton. For example, the metacarpals and metatarsals (MT) in the hands and feet form only a single growth plate at one end, and ...
Philip L. Reno, Sherrie Wallace, Sarah N. Doelp, Maria Biancaniello, Kelsey M. Kjosness   +4 more
wiley   +1 more source

Molecular Markers and Marker-Assisted Selection Provide Genetic Insights for Identifying Key Quantitative Trait Locus for Watermelon Rind Thickness. [PDF]

Int J Mol Sci
Zhao Z, Pei S, Song Y, Yang T, Gao Y, Chai H, Luan F, Zhu Z, Wang X.   +8 more
europepmc   +1 more source

Squamate ventricular cardiomyocytes: Ploidy, proliferation, and heart muscle cell size in the leopard gecko (Eublepharis macularius)

Developmental Dynamics, EarlyView.
Abstract Background While heart function is broadly conserved across vertebrates, the cellular phenotype of muscle cells (cardiomyocytes) varies across taxa and throughout ontogeny. Emerging evidence suggests that some attributes may correlate with the capacity for spontaneous cardiomyocyte replacement following injury.
Kathy Jacyniak, Karemna Barrera Jaimes, Minh Hanh Doan, Jordyn M. Chartrand, Matthew K. Vickaryous   +4 more
wiley   +1 more source

Quantitative Trait Locus Mapping Combined with RNA Sequencing Identified Candidate Genes for Resistance to Powdery Mildew in Bitter Gourd (Momordica charantia L.). [PDF]

Int J Mol Sci
Huang R, Liang J, Ju X, Huang Y, Huang X, Chen X, Liu X, Feng C.   +7 more
europepmc   +1 more source