Results 111 to 120 of about 29,995 (258)

Longitudinal data in peripheral blood confirm that PM20D1 is a quantitative trait locus (QTL) for Alzheimer's disease and implicate its dynamic role in disease progression. [PDF]

Clin Epigenetics, 2020
Wang Q, Chen Y, Readhead B, Chen K, Su Y, Reiman EM, Dudley JT.   +6 more
europepmc   +1 more source

Effect of small mapping population sizes on reliability of quantitative trait locus (QTL) mapping

AFRICAN JOURNAL OF BIOTECHNOLOGY, 2012
A limitation of quantitative trait loci (QTL) mapping is that accuracy of determining QTL position and effects  are largely determined by population size. Despite the importance of this concept, known as the "Beavis effect  there has generally been a lack of understanding by molecular geneticists and breeders.
openaire   +1 more source

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

Exploring genomic regions regulating the liver transcriptome and energy homeostasis in pigs

Animal
In pigs, energy homeostasis has an impact on meat quality and health. In a Duroc pig population, 30 quantitative trait locus ( QTL ) regions associated with fatty acid ( FA ) composition in adipose tissue, plasma, liver and muscle were previously ...
F. Llobet-Cabau, J. Liu, T. Jové-Juncà, A. Castelló, R. Quintanilla, A. Sánchez, M. Ballester, J.M. Folch   +7 more
doaj   +1 more source

Pharmacological Targets for Periodontitis: A Systematic Review of Drug‐Target Mendelian Randomisation Studies

Journal of Periodontal Research, EarlyView.
This systematic review evaluated drug‐target Mendelian randomisation studies on periodontitis. Twelve studies identified host‐response‐related targets mainly involved in inflammatory, complement, and immune pathways. Although some targets were linked to existing drugs, the evidence remains preliminary and heterogeneous, requiring replication and ...
Luigi Nibali, Jing Kang, Simon Haworth, Alessandro Polizzi, Gaetano Isola   +4 more
wiley   +1 more source

Linking genomic variation to floral trait adaptation across species boundaries

New Phytologist, EarlyView.
Examples of floral trait divergences between sister species adapted to different pollination modes. Summary Flowers are highly diverse in shape, scent, and colour and may differ strikingly even among closely related species. Floral traits experience correlational selection favouring trait combinations that maximise plant reproduction, leading to ...
Samson Acoca‐Pidolle, Carolyn A. Wessinger, Lena C. Hileman   +2 more
wiley   +1 more source

Harnessing genetic variation for grain quality from diverse wheat landraces

New Phytologist, EarlyView.
Grain protein content is usually measured on bulk samples, hiding variation between individual grains. We used hyperspectral imaging to predict protein in c. 15 000 single grains from over 500 Watkins wheat landraces grown in two environments, resolving both mean protein content and grain‐to‐grain uniformity.
Luqman B. Safdar, M. John Foulkes, Alix Cornish, Elizabeth D. Goodman, Andrew B. Riche, David Steele, Charlie Philp, Shiva Rahimitanha, Martin Whitworth, Iain R. Searle, Matt Kerton, Malcolm J. Hawkesford, Simon Griffiths, Rahul A. Bhosale, Scott A. Boden, Ian D. Fisk   +15 more
wiley   +1 more source

Excess endopolyploidy associated with cellular defects in neo‐autotetraploid Arabidopsis arenosa is in part corrected by a naturally evolved allele of CYCD3;2

New Phytologist, EarlyView.
Ploidy level distributions and endoreduplication profiles in diploid and tetraploid Arabidopsis arenosa. Summary Endopolyploidy (within‐organism polyploidy) is an often‐beneficial aspect of development. But polyploids, which have a higher baseline genome content, have been reported to have less endoreduplication than diploid relatives. Why has remained
Anis Meschichi, Marinela Dukić, Lars C. Schmid, Andreas L. Bachmann, Tadeas J. Priklopil, Hui San Tan, Kirsten Bomblies   +6 more
wiley   +1 more source

Genetic Dissection of Wheat Heterosis Identifies Candidate Genes in Biparental and Diverse Hybrid Populations

Plant Biotechnology Journal, EarlyView.
ABSTRACT Understanding how numerous heterotic quantitative trait loci (hQTL) shape heterosis and shifting from hQTL to candidate genes are central challenges. To address these challenges, we performed a systematic, genome‐wide mapping in a biparental population and a population of diverse hybrids.
Guoliang Li, Jianting Chu, Max Haupt, Yong Jiang, Jochen C. Reif   +4 more
wiley   +1 more source

Research Advances and Perspectives on Early Flowering Traits in Cucumber

Plants
Early flowering refers to the phenomenon in which the first flower appears in fewer days than normal, regardless of the sex of the flower. It is a significant feature impacting the early maturity and economic yield of cucumbers. The early flowering trait
Meidi Zhang, Ming Ma, Hong Lang, Mingliang Jiang   +3 more
doaj   +1 more source