Results 231 to 240 of about 144,128 (313)
Statistical power in genome-wide association studies and quantitative trait locus mapping
Meiyue Wang, Shizhong Xu
semanticscholar +1 more source
Abstract Leaf spot is a devastating disease in cultivated peanut (Arachis hypogaea L.) that can lead to significant yield losses without chemical controls. Multiple disease symptoms, two causal organisms, inconsistent testing environments, and genotype by environment interactions are all components that make breeding for leaf spot‐resistant peanuts ...
Cassondra Newman+8 more
wiley +1 more source
Costs of reproduction in flowering plants
Summary Costs of reproduction arise when investments into current reproduction reduce future reproductive fitness. Studies on reproductive costs use diverse approaches, including the analysis of gene expression, physiology, trade‐offs between reproduction and growth/survival, and the impact of reproductive investments on population growth.
Marcel E. Dorken+2 more
wiley +1 more source
MR analysis evaluates the bidirectional causal relationships between 91 circulating inflammatory proteins and NDDs, contingent upon three critical hypotheses: (1) Correlation hypothesis: SNPs must be strongly correlated with the exposure; (2) Independence hypothesis: SNPs should not be associated with any potential confounding factors; (3) Exclusivity ...
Ziwei Gong, Rong Cao, Hong Zhu
wiley +1 more source
Mendelian randomization (MR) and colocalization analysis were used to study the relationship between oxidative stress genes and multiple sclerosis by integrating multiple omics, and finally, two significant genes related to STAT3 and CR1 were obtained.
Yang Li+3 more
wiley +1 more source
Three Loci Affecting Variance of Body Mass Index in African Americans and Sub‐Saharan Africans
ABSTRACT Conventional genome‐wide association studies (GWAS) are designed to assess the effect of a genetic locus on phenotypic mean by genotype. Such loci explain a proportion of phenotypic variance known as narrow‐sense heritability. In contrast, variance quantitative trait loci (vQTL) are associated with the phenotypic variance by genotype.
Daniel Shriner+6 more
wiley +1 more source