Results 51 to 60 of about 144,128 (313)

An efficient hierarchical generalized linear mixed model for mapping QTL of ordinal traits in crop cultivars. [PDF]

open access: yesPLoS ONE, 2013
Many important phenotypic traits in plants are ordinal. However, relatively little is known about the methodologies for ordinal trait association studies.
Jian-Ying Feng   +5 more
doaj   +1 more source

Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk. [PDF]

open access: yes, 2019
Genetic studies of complex traits in animals have been hindered by the need to generate, maintain, and phenotype large panels of recombinant lines. We developed a new method, C.
Ben-David, Eyal   +4 more
core  

A quantitative trait locus analysis of personality in wild bighorn sheep [PDF]

open access: yes, 2013
Acknowledgments This study was supported by an Alberta Conservation Association grant to JP and Natural Sciences and Engineering Council of Canada (NSERC) discovery grants to DWC, MF and Fanie Pelletier.
Beavis   +50 more
core   +2 more sources

Novel Resampling Improves Statistical Power for Multiple-Trait QTL Mapping

open access: yesG3: Genes, Genomes, Genetics, 2017
Multiple-trait analysis typically employs models that associate a quantitative trait locus (QTL) with all of the traits. As a result, statistical power for QTL detection may not be optimal if the QTL contributes to the phenotypic variation in only a ...
Riyan Cheng   +2 more
doaj   +1 more source

Genetic Regulation of Alternative Polyadenylation Provides Novel Insights into Molecular Mechanisms Underlying Non‐small Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
Compared with the non‐risk G allele of rs9606, the risk T allele of rs9606 decreases the binding affinity of NUDT21 for LYRM4, triggering 3'UTR shortening that stabilizes LYRM4 mRNA and elevates its expression. Increased LYRM4 expression promoted malignant phenotypes of non‐small cell lung cancer (NSCLC) cells through modulating ferroptosis, supporting
Meng Jin   +11 more
wiley   +1 more source

Likelihood Ratio Test process for Quantitative Trait Loci detection. [PDF]

open access: yes, 2009
We consider the likelihood ratio test (LRT) process related to the test of the absence of QTL on the interval [0,T] representing a chromosome (a QTL denotes a quantitative trait locus, i.e. a gene with quantitative effect on a trait).
Azaïs, Jean-Marc   +2 more
core   +2 more sources

Developmental dyslexia: Genetic dissection of a complex cognitive trait [PDF]

open access: yes, 2002
Developmental dyslexia, a specific impairment of reading ability despite adequate intelligence and educational opportunity, is one of the most frequent childhood disorders.
DeFries, J., Fisher, S.
core   +2 more sources

Development and Characterization of Near-Isogenic Lines Revealing Candidate Genes for a Major 7AL QTL Responsible for Heat Tolerance in Wheat

open access: yesFrontiers in Plant Science, 2020
Wheat is one of the most important food crops in the world, but as a cool-season crop, it is more prone to heat stress, which severely affects crop production and grain quality.
Lu Lu   +7 more
doaj   +1 more source

Genomic Evaluation of Recombination in Small Highly Inbred Beef Cattle Populations

open access: yesAnimal Research and One Health, EarlyView.
The study characterizes recombination in small beef cattle populations, revealing higher rates in CGC composites compared to inbred Line 1 Herefords. It identifies significant SNP associations linked to recombination across various autosomes, highlighting complex polygenic influences, with implications for genetic diversity and breeding strategies ...
E. Hay, A. S. Ling
wiley   +1 more source

A new method for Quantitative Trait Loci Detection [PDF]

open access: yes, 2010
We consider the likelihood ratio test (LRT) process related to the test of the absence of QTL on the interval $[0,T]$ representing a chromosome (a QTL denotes a quantitative trait locus, i.e. a gene with quantitative effect on a trait).
DELMAS, Céline, Rabier, Charles-Elie
core   +1 more source

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