Results 71 to 80 of about 27,712 (261)

Recalculation of 23 mouse HDL QTL datasets improves accuracy and allows for better candidate gene analysis

Journal of Lipid Research, 2013
In the past 15 years, the quantitative trait locus (QTL) mapping approach has been applied to crosses between different inbred mouse strains to identify genetic loci associated with plasma HDL cholesterol levels.
Cheryl Ackert-Bicknell, Beverly Paigen, Ron Korstanje   +2 more
doaj   +1 more source

The receptor‐like pseudokinase LENG stimulates chilling tolerance in rice by inhibiting the activity of the OsCRPK1‐OsGF14d module

Journal of Integrative Plant Biology, EarlyView.
The rice receptor‐like pseudokinase LENG enhances chilling tolerance by binding to and suppressing the kinase activity of OsCRPK1, thereby preventing OsCRPK1‐mediated phosphorylation of the cold‐tolerance positive regulator OsGF14d. ABSTRACT Cold damage during the seedling and reproductive stages has a pronounced impact on rice development and yield ...
Shuting Yuan, Chunjue Xu, Xia Wang, Wei Yan, Xiaojie Hua, Yi Zhuang, Cuifang Wang, Changjian Wang, Yihang Gong, Jianxin Wu, Letian Chen, Xiaoyan Tang, Wenbo Pan   +12 more
wiley   +1 more source

Data-driven assessment of eQTL mapping methods

BMC Genomics, 2010
Background The analysis of expression quantitative trait loci (eQTL) is a potentially powerful way to detect transcriptional regulatory relationships at the genomic scale.
Schughart Klaus, Alberts Rudi, Michaelson Jacob J, Beyer Andreas   +3 more
doaj   +1 more source

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

The maize mitogen‐activated protein kinase kinase kinase gene ZmMAPKKK45 is associated with multiple disease resistance

New Phytologist, EarlyView.
Summary Southern leaf blight (SLB), caused by the necrotrophic fungus Cochliobolus heterostrophus, is a major foliar disease of maize (Zea mays) world‐wide. A genome‐wide association study was performed to dissect the genetic basis of SLB resistance in maize. Functional validation was performed using mutant and transgenic analyses.
Tao Zhong, Bode Olukolu, Yang Bian, Shang Xue, Randall J. Wisser, Peter S. Ojiambo, James B. Holland, Qin Yang, Peter Balint‐Kurti   +8 more
wiley   +1 more source

Genetic improvement of FHB and DON resistance by combining the Fhb1 gene with additional resistance QTL in winter wheat population

The Plant Genome
Fusarium head blight (FHB) of wheat (Triticum aestivum L.), caused by Fusarium graminearum, is a major wheat disease that causes significant yield and quality loss.
Anjan Neupane, Ljiljana Tamburic‐llincic, Anita Brûlé‐Babel, Curt A. McCartney   +3 more
doaj   +1 more source

Distinct Roles for Two Chromosome 1 Loci in Ethanol Withdrawal, Consumption, and Conditioned Place Preference

Frontiers in Genetics, 2018
We previously identified a region on chromosome 1 that harbor quantitative trait loci (QTLs) with large effects on alcohol withdrawal risk using both chronic and acute models in mice. Here, using newly created and existing QTL interval-specific congenic (
Laura B. Kozell, Deaunne L. Denmark, Nicole A. R. Walter, Kari J. Buck   +3 more
doaj   +1 more source

Quantitative trait locus (QTL) analysis and fine-mapping for Fusarium oxysporum disease resistance in Raphanus sativus using GRAS-Di technology. [PDF]

Breed Sci, 2023
Ezeah CSA, Shimazu J, Kawanabe T, Shimizu M, Kawashima S, Kaji M, Ezinma CO, Nuruzzaman M, Minato N, Fukai E, Okazaki K.   +10 more
europepmc   +1 more source

Genetic and Molecular Determinants of Familial Transmission of Skeletal Malocclusions

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT Families studies conducted in different ethnic populations worldwide have helped elucidate the molecular and genetic factors involved in the development of skeletal class III malocclusion. Therefore, the aim of this study is to provide an updated summary.
Alexandra Dehesa‐Santos, Lucia Carreño‐Gomez, Rosa Yañez‐Vico, Alejandro Iglesias‐Linares   +3 more
wiley   +1 more source

Four additional mouse crosses improve the lipid QTL landscape and identify Lipg as a QTL gene[S]

Journal of Lipid Research, 2009
To identify genes controlling plasma HDL and triglyceride levels, quantitative trait locus (QTL) analysis was performed in one backcross, (NZO/H1Lt × NON/LtJ) × NON/LtJ, and three intercrosses, C57BL/6J × DBA/2J, C57BL/6J × C3H/HeJ, and NZB/B1NJ × NZW ...
Zhiguang Su, Naoki Ishimori, Yaoyu Chen, Edward H. Leiter, Gary A. Churchill, Beverly Paigen, Ioannis M. Stylianou   +6 more
doaj   +1 more source