Results 31 to 40 of about 3,276,882 (200)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Finding Key Nodes in Complex Networks Through Quantum Deep Reinforcement Learning

Entropy
Identifying key nodes in networks is a fundamental problem in network science. This study proposes a quantum deep reinforcement learning (QDRL) framework that integrates reinforcement learning with a variational quantum graph neural network, effectively ...
Juechan Xiong, Xiao-Long Ren, Linyuan Lü   +2 more
doaj   +1 more source

Quantum homotopy perturbation method for nonlinear dissipative ordinary differential equations

New Journal of Physics, 2021
While quantum computing provides an exponential advantage in solving linear differential equations, there are relatively few quantum algorithms for solving nonlinear differential equations.
Cheng Xue, Yu-Chun Wu, Guo-Ping Guo
doaj   +1 more source

CUDA Quantum

, 2023
<p>CUDA Quantum is now available <a href="https://pypi.org/project/cuda-quantum/">on PyPI</a>! For the initial PyPI release, the NVIDIA multi-gpu and tensornet backends are not yet included. Check out our Docker images <a href="https:
The CUDA Quantum development team
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Fixed-Point Grover Adaptive Search for Quadratic Binary Optimization Problems

IEEE Transactions on Quantum Engineering
In this article, we study a Grover-type method for quadratic unconstrained binary optimization (QUBO) problems. For an $n$-dimensional QUBO problem with $m$ nonzero terms, we construct a marker oracle for such problems with a tunable parameter, $\Lambda \
Akos Nagy, Jaime Park, Cindy Zhang, Atithi Acharya, Alex Khan   +4 more
doaj   +1 more source

In situ upgrade of quantum simulators to universal computers [PDF]

, 2018
Quantum simulators, machines that can replicate the dynamics of quantum systems, are being built as useful devices and are seen as a stepping stone to universal quantum computers.
Benjamin Dive, Alexander Pitchford, Burgarth, Daniel, Florian Mintert, Daniel Burgarth, Dive, B, Mintert, Florian, Pitchford, Alexander   +7 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

NISQ-compatible approximate quantum algorithm for unconstrained and constrained discrete optimization

, 2023
Funding Information: We thank Dr. Margarita Veshchezerova, Dr. Alexey Melnikov, Vishal Shete, and Karan Pinto for their valuable discussions and suggestions.
Kreidich, I., Melnikov, Ar A., Podobrii, M., Nuriev, B., Iudin, S., Termanova, A., Mansell, C. W., Vinokur, V. M., Pakhomchik, A. I., Perelshtein, M. R.   +9 more
core   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source