Results 1 to 10 of about 219 (64)
Angewandte Chemie, Volume 138, Issue 12, 16 March 2026.Given the prominence of 19F‐bioNMR in structural research, fluorinated glycans hold enormous potential in glycomimetic frameshift design. However, challenges associated with the stereocontrolled synthesis of these disruptive actors continue to frustrate advances. To address this, the automated synthesis of selectively C‐2 fluorinated glycans related to
James Suri +6 more
wiley +2 more sources
Benzoyl‐Xanthenoxanthenes: Versatile Chromophores for Light‐Engaging Applications
Angewandte Chemie, Volume 138, Issue 7, 9 February 2026.Oxidatively stable benzoyl‐fused peri‐xanthenoxanthene ribbons with NIR emission were synthesized. Their good spectral overlap enabled cascaded Förster resonance energy transfer (FRET) antennae in a nematic liquid crystal phase, achieving directional energy transfer.
Cristian De Luca +10 more
wiley +2 more sources
Donor–Acceptor Pentacene Analogues With Near‐Infrared Emission and Tunable Aromaticity
Angewandte Chemie International Edition, EarlyView.Air‐ and photostable heterocyclic pentacene analogues with donor and acceptor groups flanking a para‐quinodimethane core exhibit large dipole moments, narrow bandgaps, reversible redox behavior, and NIR‐I to NIR‐II absorption and emission with pronounced solvatochromism.
Krzysztof Nowak +6 more
wiley +1 more source
ChemBioChem, Volume 27, Issue 8, April 2026.We introduce uracil–triazole–pyrene peptidomimetics whose tunable peptide linkers precisely control light emission, copper binding, and interactions with DNA and RNA. Fine structural adjustments unlock selective biomolecular recognition and striking metal‐ and membrane‐responsive fluorescence, paving the way for a new generation of multifunctional ...
Dijana Pavlović Saftić +2 more
wiley +1 more source
Design, Synthesis, and Structural Evolution of Pseudo‐Natural Product IDO1 Inhibitors and Degraders
Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.The combination of bicyclic monoterpene‐ and pyrrolidine‐alkaloid fragments yields novel pseudo‐natural products. Biological characterization revealed that these iDegs are inhibitors and degraders of indoleamine‐2,3‐dioxygenase. Abstract Terpenoid alkaloids are derived from the fusion of structurally diverse terpenoid‐ and alkaloid moieties.
Xiu‐Fen Cheng +19 more
wiley +2 more sources
Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.We report a triply responsive artificial ion channel, showing tuneable activity, and responsive to three distinct stimuli ‐ light, pH, and ligand – which we use to formulate an AND to OR switchable molecular logic gate. Abstract Ion channels are ubiquitous in Nature, performing complex and essential tasks in our bodies. Synthetic chemists have begun to
Javid Ahmad Malla +5 more
wiley +2 more sources
Advanced Functional Materials, Volume 36, Issue 26, 30 March 2026.A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo +7 more
wiley +1 more source
Photocaged and Water‐Soluble Glucose Functionalization for Spatiotemporal Acidification Pathways
Helvetica Chimica Acta, Volume 109, Issue 3, March 2026.Light‐controlled glucose release from a water‐soluble coumarin photocage enables spatiotemporal acid generation in enzyme‐driven chemical reaction networks. ABSTRACT The spatiotemporal control of complex molecular systems, such as chemical reaction networks (CRNs), requires reagents and reactive species that can be activated both efficiently and ...
Nikolai Hempel +2 more
wiley +1 more source
Macromolecular Chemistry and Physics, Volume 227, Issue 5, 13 March 2026.PCL‐PEG based ACN thin films provide a highly tunable biointerface, where PEG content governs morphology, protein adsorption, and cellular responses. PEG‐lean films support fibroblast adhesion and proliferation, while PEG‐rich films are non‐cell‐adhesive with low protein adsorption, reversible by dECM coating.
Yasmina El‐Faramawi +8 more
wiley +1 more source
Angewandte Chemie, Volume 138, Issue 1, 2 January 2026.An iron‐based, enzyme‐triggered CO‐releasing molecule (ET‐CORM) is site‐specifically conjugated to the antibody trastuzumab. This novel ET‐CORM‐antibody conjugate releases carbon monoxide upon cleavage by the tumor‐associated protease cathepsin B. The construct enables selective intracellular CO delivery to HER2‐overexpressing and CatB‐expressing cells,
Inga Černauskienė +7 more
wiley +2 more sources