Results 221 to 230 of about 250,916 (308)

Balancing Stealth and Targetability: cCPP‐ and PEG‐Modified Liposomes for the Targeted Delivery of Anti‐HER2 Nanobodies

Advanced Science, EarlyView.
This study addresses the rapid renal clearance of anti‐HER2 nanobodies by developing specialized liposomal carriers. It details the formulation of dual modified liposomes, demonstrating how PEGylation preserves structural integrity and cell‐penetrating peptides enhance cellular interaction.
Giulia Pander, Maria del Pilar Palacios Cisneros, Clara Certa, Megan Stierli, Katharina Beck, Nicolas Färber, Lisa Blank, Fiona Tanner, Eric Mühlberg, Sabrina Wohlfart, Christian Kleist, Jörg Huwyler, Gert Fricker, Walter Mier, Philipp Uhl   +14 more
wiley   +1 more source

Comparative analysis of natural and synthetic surfactant adsorption by quartz minerals: an experimental study. [PDF]

Sci Rep
Shirali A, Ebrahimi M, Hemmati-Sarapardeh A, Ranjbar M, Schaffie M.   +4 more
europepmc   +1 more source

Enhancing Biogenic Formic Acid Production in the Modified OxFA Process by Acetonitrile Addition

Advanced Science, EarlyView.
In this study, the beneficial effect of using acetonitrile as a co‐solvent in the modified OxFA process is shown, outperforming methanol, demonstrating improved reaction kinetics combined with high selectivity for the HPA‐2 (H5PV2Mo10O40) catalyzed oxidation of xylose to FA.
Jan‐Dominik H. Krueger, Pegah Saedi, Maximilian J. Poller, Alberto Collauto, Jason P. Hallett, David Robinson, Maxie M. Roessler, Jakob Albert   +7 more
wiley   +1 more source

Imagining Futuretypes| The Aliens Are Us: The Limitations That The Nature of Fiction Imposes on Science Fiction About Aliens

International Journal of Communication, 2016
Gideon Lichfield, Aubrie Adams, Lonny J Avi Brooks   +2 more
doaj  

Granitic intrusions enhance strain localization and rapid mantle exhumation along an oceanic detachment fault. [PDF]

Sci Adv
Poulaki EM, Bickert M, Vannucchi P, Shuck BD, Akizawa N, Pandey A, Morishita T, Sanfilippo A, Cunningham EH, Barnes JD, Garber JM, Nistor C, Bernard R, Tribuzio R, Loocke M, Abe N, Di Stefano A, Filina IY, Fu Q, Gontharet SBL, Kearns LE, Koorapati RK, Lei C, Loreto MF, Magri L, Menapace W, Pavlovics VL, Pezard PA, Rodriguez-Pilco MA, Zhao X, Pérez-Gussinyé M, Garrido CJ, Ranero CR, Estes ER, Malinverno A, Zitellini N.   +35 more
europepmc   +1 more source

Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy

Advanced Science, EarlyView.
MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang, Shengxin Lu, Guangyong Zheng, Shensuo Li, Hongyu Chen, Mei Hong, Xiangru Zhou, Ruotian Tang, Ye Wu, Weidong Zhang, Dong Lu, Xin Luan   +11 more
wiley   +1 more source

Reliability of quartz-hosted melt inclusions and discrete rhyolite reservoirs revealed by H isotopes, trace elements, and volatiles. [PDF]

Sci Adv
Hickernell SM, Pamukçu AS, Monteleone BD.   +2 more
europepmc   +1 more source

A Plug‐and‐Play Platform for Customizing Multivalent Degraders and Degrader‐Drug Conjugates

Advanced Science, EarlyView.
Membrane proteins remain challenging targets for conventional TPD approaches. Here, the authors develop UPTAB, a modular platform leveraging ultrahigh‐affinity orthogonal Im/CL protein pairs for lysosomal degradation of membrane proteins. Mono‐targeted (Type‐I), dual‐targeted (Type‐II), and tri‐targeted (Type‐III) UPTABs enable simultaneous degradation
Mengqing Zhao, Yan Deng, Jianjian Han, Yong Xie, Kai Bao, Lixin Ma, Lilong Liu, Wuxiang Mao   +7 more
wiley   +1 more source

Sediment fingerprints: A forensic technique using quartz sand grains - A response

, 2006
Bull, PA, Morgan, RM
core  

On the origin of our fascination with crystals. [PDF]

Front Psychol
García-Ruiz JM, de la Rosa T, Delval I, Bustelo G.   +3 more
europepmc   +1 more source