Results 41 to 50 of about 1,747 (185)

Dynamic Regulation of Endogenous Transcription Factor Hubs at Single‐Molecule Resolution

Advanced Science, EarlyView.
This study combines single‐molecule microscopy and genome editing to characterize the dynamic behaviors of endogenous oncofusion transcription factor EWS::FLI1 in Ewing sarcoma cells. EWS::FLI1 forms neomorphic hubs that dynamically assemble and dissolve. The hubs are regulated during mitosis, by RNA, and by specific chemicals.
Shawn Yoshida, Yanghao Zhong, Akiko Kumagai, William G. Dunphy, Shasha Chong   +4 more
wiley   +1 more source

Subaru High-z Exploration of Low-luminosity Quasars (SHELLQs). XXI. Candidate Red Quasars at z ≥ 6 from Near-infrared Photometry

The Astrophysical Journal
We present an analysis of near-infrared photometry of 59 quasars at 5.83  −24 mag) of the sample. This luminosity trend may support the idea that red quasars represent an evolutionary stage preceding unobscured quasars, often invoked in the merger-driven
Ryo Iwamoto, Yoshiki Matsuoka, Masatoshi Imanishi, Kazushi Iwasawa, Takuma Izumi, Nobunari Kashikawa, Toshihiro Kawaguchi, Mahoshi Sawamura, Michael A. Strauss, Ayumi Takahashi, Yoshiki Toba   +10 more
doaj   +1 more source

Feasibility Study for Application of Digitized Henize Mt. Wilson Michigan Southern Sky Hα$$ \boldsymbol{\alpha} $$ Survey Low‐Dispersive Spectral Plates for Searches for Anomalous and Highly Redshifted Objects

Astronomische Nachrichten, EarlyView.
ABSTRACT The goal of this study is to confirm the feasibility of the use of digitized low dispersive MtWilson Michigan Southern Sky Hα$$ \alpha $$ survey astronomical photographic plates for modern astrophysical research. The detection of highly redshifted objects, such as early galaxies and quasars, is fundamental to understanding the universe's ...
Tauseef Ahmad Zafar, René Hudec, Marta Mara Merono Vidagany, Fehmi Mejri   +3 more
wiley   +1 more source

The prognostic value of tumour budding for survival in stage II and III colorectal cancer: a systematic review and meta‐analysis

Histopathology, EarlyView.
This meta‐analysis demonstrates that high‐grade tumour budding is an independent prognostic factor in stage II–III colorectal cancer, associated with significantly worse disease‐free survival, overall survival and cancer‐specific survival. Aims Tumour budding (TB) has been recognized as an additional prognostic factor in the TNM (2017) and WHO (2019 ...
Yao Shu, Heng Zhang, Alessandro Lugli, Femke Simmer, Iris D. Nagtegaal   +4 more
wiley   +1 more source

Red Type-1 Quasars after Cosmic Noon and Impact on L UV-related Quasar Statistics

The Astrophysical Journal
Over the past decades, nearly a million quasars have been explored to shed light on the evolution of supermassive black holes and galaxies. The ultraviolet-to-optical spectra of type-1 quasars particularly offer insights into their black hole activities.
Yongjung Kim, Dohyeong Kim, Myungshin Im, Minjin Kim   +3 more
doaj   +1 more source

Predicting the Yields of z > 6.5 Quasar Surveys in the Era of Roman and Rubin

The Astrophysical Journal, 2023
About 70 luminous quasars discovered at z > 6.5 are strongly biased toward the bright end, thus not providing a comprehensive view of quasar abundance beyond the cosmic dawn. We present the predicted results of the Roman/Rubin high-redshift quasar survey,
Wei Leong Tee, Xiaohui Fan, Feige Wang, Jinyi Yang, Sangeeta Malhotra, James E. Rhoads   +5 more
doaj   +1 more source

Revisiting the life cycle of Margalefidinium polykrikoides Group III

Journal of Phycology, EarlyView.
Abstract Dinoflagellates produce cysts as a strategy to withstand environmental stressors, with nutrient depletion generally considered a key trigger for cyst production. Resting cysts are thick‐walled, typically composed of one to several layers, and characterized by a prolonged dormancy period.
Eduardo Pérez‐Vega, Kenneth N. Mertens, Pjotr Meyvisch, Margaret R. Mulholland   +3 more
wiley   +1 more source

Shedding New Light on Weak Emission-line Quasars in the C iv–Hβ Parameter Space

The Astrophysical Journal, 2023
Weak emission-line quasars (WLQs) are a subset of type 1 quasars that exhibit extremely weak Ly α + N v λ 1240 and/or C iv λ 1549 emission lines. We investigate the relationship between emission-line properties and accretion rate for a sample of 230 ...
Trung Ha, Cooper Dix, Brandon M. Matthews, Ohad Shemmer, Michael S. Brotherton, Adam D. Myers, Gordon T. Richards, Jaya Maithil, Scott F. Anderson, W. N. Brandt, Aleksandar M. Diamond-Stanic, Xiaohui Fan, S. C. Gallagher, Richard Green, Paulina Lira, Bin Luo, Hagai Netzer, Richard M. Plotkin, Jessie C. Runnoe, Donald P. Schneider, Michael A. Strauss, Benny Trakhtenbrot, Jianfeng Wu   +22 more
doaj   +1 more source

Comparative Effectiveness Analysis of Phase 3 Clinical Trials in Moderately to Severely Active Inflammatory Bowel Disease Reveals Increased Harm From Placebo and Challenges Equipoise

JCC Plus, Volume 1, Issue 5, September 2026.
Across 47 Phase 3 trials in Crohn's disease and ulcerative colitis, placebo exposure was associated with measurable harm. Disease exacerbation events showed the greatest excess risk, with one additional exacerbation occurring for every 8–13 patients assigned to placebo rather than active therapy.
Joëlle St‐Pierre, Zachary D. Fine, Evan N. Fear, Jeremy A. Klein, Natalie K. Choi, David T. Rubin   +5 more
wiley   +1 more source

Impact of Radio-mode Feedback on the Covering Fraction of the Circumgalactic Medium of Quasars

The Astrophysical Journal
Utilizing data from the Low-Frequency Array Two-meter Sky Survey and the Sloan Digital Sky Survey, we assemble a sample of 1469 projected quasar pairs with detected radio emissions from foreground quasars, as well as a control sample of 5846 pairs ...
Wen-Qiang Liang, Zhi-fu Chen, Rui-Jing Lu, Jing Li, Zhe-Geng Chen   +4 more
doaj   +1 more source