Results 31 to 40 of about 139,436 (260)
Dizhi lixue xuebao, 2023 The Nanyuan–Tongxian fault is the boundary fault between the Beijing depression and the Daxing uplift, also the primary seismic-controlling fault of the Beijing M \begin{document}$ 6{\dfrac{1}{2}}$\end{document} earthquake in 1665.
NIU Wenzhi +8 more
doaj +1 more source
Journal of Marine Science and Engineering, 2022 Koločep bay is a 30 km elongated karst basin located between the Elafiti Islands and the mainland with a NW–SE general direction. The bay lies within the seismically active southern Dalmatia zone.
Dragana Šolaja +9 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan +3 more
wiley +1 more source
Agrociencia Uruguay, 2022 The Chuy Formation is characterized by up to 135 m of an alternation of green pelites and fine to coarse sandstones with sparse invertebrate fossils. The marine deposits are interbedded with continental, loessic deposits of the Libertad Formation and ...
Eduardo Castiglioni +3 more
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Geologija, 2020 Geomorphological and geological mapping have long been used to study the glacial history of the Slovenian Alps, but many uncertainties remain regarding the time and extent of Pleistocene glaciations there.
Petra JAMŠEK RUPNIK +2 more
doaj +1 more source