Results 41 to 50 of about 162,949 (204)

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Quaternary research in New Zealand since 2000: an overview [PDF]

, 2012
With the AQUA milestone of 30 years it seems an appropriate time to review the progress and achievements of Quaternary research in New Zealand. This article highlights some of the major achievements since the formal review of New Zealand’s Quaternary ...
Lowe, David J., Bostock, Helen C., Newnham, Rewi M., Almond, Peter C.   +3 more
core  

More water-soluble brown carbon after the residential “coal-to-gas” conversion measure in urban Beijing

npj Climate and Atmospheric Science, 2023
The implementation of air pollution reduction measures has significantly reduced the concentration of atmospheric fine particles (PM2.5) in Beijing, among which the “coal-to-gas” conversion measures may play a crucial role.
Wei Yuan, Ru-Jin Huang, Jincan Shen, Kai Wang, Lu Yang, Ting Wang, Yuquan Gong, Wenjuan Cao, Jie Guo, Haiyan Ni, Jing Duan, Thorsten Hoffmann   +11 more
doaj   +1 more source

A Continuous Seismostratigraphic Framework for the Western Svalbard-Barents Sea Margin Over the Last 2.7 Ma: Implications for the Late Cenozoic Glacial History of the Svalbard-Barents Sea Ice Sheet

Frontiers in Earth Science, 2021
Here we present a high-resolution, continuous seismostratigraphic framework that for the first time, connects the over 1,000 km long western Svalbard-Barents Sea margin and covers the last ∼2.7 million years (Ma).
Nikolitsa Alexandropoulou, Monica Winsborrow, Karin Andreassen, Andreia Plaza-Faverola, Pierre-Antoine Dessandier, Pierre-Antoine Dessandier, Rune Mattingsdal, Nicole Baeten, Jochen Knies, Jochen Knies   +9 more
doaj   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Patterns of shelf margin clinoform: control of the development of deep-water sedimentary systems

Frontiers in Marine Science
The clinothem is the fundamental element of basin infill and plays an important role in the source-to-sink system of deep-water basins. In this study, which is based on 2D and 3D seismic data, the spatiotemporal evolution of clinothems and depositional ...
Tong Li, Tong Li, Tong Li, Detian Yan, Detian Yan, Detian Yan, Entao Liu, Junfeng Zhang, Junfeng Zhang, Junfeng Zhang, Xiaosong Wei, Xiaosong Wei, Xiaosong Wei, Zeyu Lu, Zeyu Lu, Zeyu Lu, Xudong Lin   +16 more
doaj   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

Mid- to Late-Quaternary evolution of the Wilderness Barrier dunes, South Africa [PDF]

, 2011
Barrier dunes represent potentially long-term, but complex, archives of coastal evolution. The examples occupying the Wilderness embayment, on the southern Cape coast of South Africa, form a regionally unique system of three shore-parallel barriers ...
Dunajko, Adam C.
core   +4 more sources

The late quaternary history of Southern hemisphere mediterranean climate regions in the Western Cape, South Africa, and Southwestern Australia [PDF]

, 2010
Includes abstract.Includes bibliographical references (leaves 215-241).The study is focused on four study sites, two in the Western Cape, namely the Bruno section and Lake Michelle and two in southwestern Australia, namely Wambellup Swamp and Devil's ...
Smith, Brett
core   +1 more source

Synthesis, characterization, and drug delivery property of 2-N-carboxymethyl-6-O-diethylaminoethyl-chitosan

e-Polymers, 2013
A novel route is demonstrated for the synthesis of 2-N-carboxymethyl-6- O-diethylaminoethyl-chitosan (DEAE-CMC) by incorporation of carboxymethyl groups as hydrophilic moieties to the C2-NH2, and diethylaminoethyl groups as hydrophobic moieties to the C6-
Zhang Aidi, Ding Derun, Ren Jicun, Zhu Xiangli, Yao Youhong   +4 more
doaj   +1 more source