Results 81 to 90 of about 162,949 (204)
History of the Quaternary vegetation sciences
, 2023 Under the roof of geology, palaeontology is a strong branch within which the discipline of palaeobotany has been established. This discipline encompasses the evolution and differentiation of plant families and species. The term was also initially applied
Behre, Karl-Ernst, Lang, Gerhard
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Natural and human induced late quaternary environmental change on the Noordhoek Valley, Cape Town, South Africa [PDF]
, 2004 Includes bibliographical references (leaves 130-139).This research project attempts to determine the relative influences of climate, sea level changes and human activities during the period of sediment accumulation in the Noordhoek basin in the ...
Akunji, E U
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Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
The Milankovitch Theory Revisited to Explain the Mid-Pleistocene and Early Quaternary Transitions
AtmosphereThe theory of orbital forcing as formulated by Milankovitch involves the mediation by the advance (retreat) of ice sheets and the resulting variations in terrestrial albedo. This approach poses a major problem: that of the period of glacial cycles, which
Jean-Louis Pinault
doaj +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Advances in Quaternary tephrostratigraphy and tephrochronology in New Zealand [PDF]
, 1999 This paper summarises recent studies on Quaternary tephra deposits in New Zealand, and refers to a range of tephrochronological applications including sequence stratigraphy, palaeoclimatic reconstruction, and archaeology.
Lowe, David J., Newnham, Rewi M.
core
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Geoscience Data JournalQuaternary unconsolidated sediments are pronouncedly widespread features on the planetary surface, documenting significant geological signals of earth surface processes, climate change and biogeochemical cycles. The extensive unconsolidated deposits play
Yalige Bai +4 more
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