Results 171 to 180 of about 22,487 (287)

Emerging research directions in nanoparticle‐based foam control for bioprocessing: a bibliometric approach

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract Overfoaming remains a critical challenge in industrial bioprocesses, compromising mass transfer, operational stability, and downstream efficiency in bioreactors and wastewater treatment systems. This study provides a bibliometric and scientometric assessment of nanoparticle‐enabled foam control to map technological trends and identify research
Antonio Átila Menezes Ferreira   +6 more
wiley   +1 more source

Metabolic fate of drugs of abuse and new psychoactive substances: A pilot study on a novel workflow using a zebrafish embryo model combined with human microdosing

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study was to develop a novel workflow to identify human urine biomarkers for drugs of abuse and new psychoactive substances. Metabolites of amphetamine, cocaine, LSD, MDMA, methamphetamine, THC, MDMB‐CHMICA, and MDPPP were first identified in a zebrafish embryo (ZE) metabolism study followed by comparison to most abundant human ...
Simon K. Wellenberg   +7 more
wiley   +1 more source

Overcoming intranasal delivery barriers with ultrastable polyzwitterionic siRNA nanocages for enhanced glioblastoma therapy

open access: yesBMEMat, EarlyView.
A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie   +12 more
wiley   +1 more source

Machine learning‐assisted clone selection for intensified cell culture processes

open access: yesBiotechnology Progress, EarlyView.
Abstract Intensified fed‐batch processes are becoming increasingly prevalent among biomanufacturers due to their superior space–time yields relative to traditional, non‐intensified fed‐batch processes. However, the shift towards intensified manufacturing has unexpectedly made optimal clone selection more challenging.
Nicolas Wolnick   +6 more
wiley   +1 more source

Status and future of recombinant adeno‐associated virus vector manufacturing

open access: yesBiotechnology Progress, EarlyView.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source

Functionalized Organic Lithium Salt Enables Flexible Solid‐State Electrolytes With Dual‐Ion Channels for Safe Li Metal Batteries

open access: yesCarbon Energy, EarlyView.
Here, we design a flexible and non‐flammable solid‐state electrolyte with hierarchical dual‐ion conductive channels. The engineered electrolyte combines continuous organic conductive‐phase pathways for fast bulk Li+ transport and dynamic polymer networks for interfacial ion hopping, achieving unprecedented room temperature conductivity (> 1 mS cm−1 ...
Yijing Liu   +7 more
wiley   +1 more source

1D/3D Heterojunction for High‐Efficiency Hole‐Transport Layer‐Free Carbon‐Based Wide‐Bandgap Perovskite Solar Cells

open access: yesCarbon Energy, EarlyView.
By modifying wide‐bandgap high‐Cs perovskite surfaces with quaternary ammonium salts of varying alkyl‐chain lengths, tetrapropylammonium bromide (TPABr) is shown to successfully construct a 1D/3D heterojunction. This structure effectively passivates interface defects and optimizes energy level alignment, achieving a champion efficiency of 20.14% with ...
Lingcong Li   +9 more
wiley   +1 more source

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