Results 71 to 80 of about 22,487 (287)

Detection of The Quaternary Ammonium Compound Antiseptic Resistance Gene (qac A/B qac C and qac E gene) In Pseudomonas Aeruginosa Recovered from Topical Wound Infection

open access: yes, 2023
Background: Quaternary ammonium compounds (QACs) have represented one of the most visible and effective classes of antiseptics and disinfectants substances that used in different parts of life including food production, water treatment and healthcare ...
Hassan, Jabbar S.   +5 more
core   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao   +11 more
wiley   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

open access: yesAdvanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu   +18 more
wiley   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

open access: yesAdvanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang   +9 more
wiley   +1 more source

Zebrafish as a model for assessing biocide toxicity: A comprehensive review

open access: yesToxicology Reports
The utilization of biocides in a myriad of products has become a widespread and critical practice in recent years. Among these, quaternary ammonium compounds, polyhexamethylene, parabens, and triclosan are notably prevalent across various industrial ...
Ali Pourshaban-Shahrestani   +2 more
doaj   +1 more source

(R)-(+)-3-Hydroxy-2-methoxycarbonyl-8-methyl-8-azoniabicyclo[3.2.1]octane l-bitartrate

open access: yesActa Crystallographica Section E, 2008
(RS)-(±)-2-Methoxycarbonyl-3-tropinone is an important intermediate for the preparation of cocaine and its derivatives. The molecule in the title compound, C10H16NO3+·C4H5O6−, is present as the enol tautomer.
Jian-Bing Yu   +3 more
doaj   +1 more source

Evaluation of Third Generation Quaternary Ammonium Compounds for the Sterilisation of Operation Theatre

open access: yes, 2023
Sterilisation of operation theatre is the global method in the prevention of surgical wound infections. In recent years the first- and second-generation compounds are replaced by the third-generation quaternary ammonium compounds.
Thenmozhivalli PR   +3 more
core   +1 more source

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

open access: yesAdvanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang   +6 more
wiley   +1 more source

X-Ray Diffraction Studies of Quaternary Ammonium Treated Montmorillonite

open access: yes, 1962
This study was undertaken to investigate the water-proofing effect of quaternary ammonium ions on montmorillonite. The interaction between a quaternary ammonium ion and montmorillonite was investigated on the basis of basal spacings and electrokinetic ...
Kesaree, M., Rosauer, E., Demirel, T.
core  

Streptavidins Coordinate Biotin Sequestration and Self‐Resistance Within a Biotin‐Pathway Antibiotic Network

open access: yesAdvanced Science, EarlyView.
A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa   +8 more
wiley   +1 more source

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