Results 141 to 150 of about 78,150 (329)

EVALUATION OF THE ANTIMICROBIAL EFFECTS OF NEW HETEROCYCLIC BIS-QUATERNARY AMMONIUM COMPOUNDS ON BIOFILMS

Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, 2016
Considering the well-known mechanism of adaptable resistance of microorganisms to chemical compounds through biofilms formation and the widespread use of N-heterocyclic quaternary ammonium salts (QAC) as disinfectants, in this study we have evaluate the ...
OANA E. CONSTANTIN, BIANCA FURDUI, GABRIELA BAHRIM, RODICA M. DINICA   +3 more
doaj  

A novel and chemoselective process of N-alkylation of aromatic nitrogen compounds using quaternary ammonium salts as starting material [PDF]

, 2017
Artículo Internacional Open AccesThe process of N-alkylation of several pyrroles, indoles, and derivative heterocycles is herein described, using quaternary ammonium salts as the source of an alkylating agent.
Corona Becerril, David, Corona Becerril, David, FUENTES BENITES, MARIA PAULINA AYDEE GRACIA, FUENTES BENITES, MARIA PAULINA AYDEE GRACIA, GARCIA MONROY, RICARDO, GARCIA MONROY, RICARDO, GONZALEZ CALDERON, DAVIR, GONZALEZ CALDERON, DAVIR, GONZALEZ GONZALEZ, CARLOS A., GONZALEZ GONZALEZ, CARLOS A., GONZALEZ ROMERO, CARLOS, GONZALEZ ROMERO, CARLOS, MEJIA VEGA, JUAN JAVIER, MEJIA VEGA, JUAN JAVIER, TAMARIZ MASCARUA, JOAQUIN, TAMARIZ MASCARUA, JOAQUIN   +15 more
core  

AI‐Based D‐Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug‐Resistant Bacterial Infection

Advanced Science, EarlyView.
This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao, Qingzhou Kong, Haifan Gong, Lixiang Li, Jialu Fu, Boyao Wan, Peizhu Wang, Xiaojuan Li, Yue Wang, Jinghui Zhang, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +14 more
wiley   +1 more source

Inhibitory effects of quaternary ammonium compounds on lysosomal degradation of endogenous proteins.

, 1989
Yoshio Matsumoto, Takafumi Watanabe, Tetsuya Suga, Hideo Fujitani   +3 more
openalex   +2 more sources

Evaluation of Reduced Susceptibility to Quaternary Ammonium Compounds and Bisbiguanides in Clinical Isolates and Laboratory-Generated Mutants of Staphylococcus aureus [PDF]

, 2013
Leonardo Furi, Maria Laura Ciusa, Daniel R. Knight, Valeria Di Lorenzo, Nadia Tocci, Daniela Cirasola, Lluís Aragonès, Joana Rosado Coelho, Ana T. Freitas, Emmanuela Marchi, Laura Mocé, Pilar Visa, John Blackman Northwood, Carlo Viti, Elisa Borghi, Graziella Orefici, Ian Morrissey, Marco R. Oggioni   +17 more
openalex   +1 more source

Engineering Charge Heterogeneity in COF/Graphene Hydrogels for Salt‐Resistant Solar Evaporation

Advanced Science, EarlyView.
Hetero‐charged COF/graphene hydrogel (HCG‐1) with spatially separated cationic and anionic domains is engineered to achieve salt‐resistant solar evaporation. This unique charge architecture regulates Na⁺ and Cl− distribution, promotes intermediate‐water formation and effectively suppresses salt crystallization, enabling stable solar evaporation in ...
Shuwen Jia, Yanrui Li, Guangyu He, Xinda Nan, Xiao Xiao, Chuan Wang, Arne Thomas, Changxia Li   +7 more
wiley   +1 more source

CRISPR‐Cas9‐Loaded Theranostic Liposomes for Enhancing Radiosensitization of Prostate Cancer through POLD4 Gene Editing under Real‐Time MRI Monitoring

Advanced Science, EarlyView.
This study identifies POLD4 as a potential prostate cancer radiosensitization target through transcriptome sequencing. By encapsulating POLD4‐targeted CRISPR/Cas9 plasmids and USPIONs in cationic liposomes, an MRI‐monitored gene‐editing platform is established.
Xuhui Fan, Ruru Zhang, Linjun Yang, Shixiong Chen, Meijuan He, Yongqiang Wang, Linjie Huang, Jianfeng Zeng, Shuwang Wu, Mingyuan Gao, Han Wang   +10 more
wiley   +1 more source

Quaternary Ammonium Compounds in Medicinal Chemistry, II [PDF]

Journal of Pharmacy and Pharmacology, 1962
P F, D'ARCY, E P, TAYLOR
openaire   +4 more sources

Gut Microbe‐Driven Resistance Mechanisms in Propylea Japonica: Insights from Horizontal Gene Transfer and Oxidative Phosphorylation

Advanced Science, EarlyView.
Acinetobacter regulates dinotefuran tolerance in Propylea japonica by mediating the expression of the horizontally transferred gene PjDUF1. Abstract Insect–microbial symbiont relationships are widespread in nature and often involve lateral gene transfer.
Ningbo HuangFu, Xiangzhen Zhu, Zhijuan Tang, Li Wang, Kaixin Zhang, Dongyang Li, Jichao Ji, Jinjie Cui, Zhaojiang Guo, Junyu Luo, Xueke Gao   +10 more
wiley   +1 more source

Determination of 25 quaternary ammonium compounds in sludge by liquid chromatography-mass spectrometry. [PDF]

Anal Sci, 2023
Shu M, Ding D, Asihaer Y, Xu Z, Dou Y, Guo L, Dan M, Wang Y, Hu Y.   +8 more
europepmc   +1 more source