Results 181 to 190 of about 72,446 (353)

Bioinspired Claw‐Engaged Adhesive Microparticles Armed with γGC Alleviate Ulcerative Colitis via Targeted Suppression of Macrophage Ferroptosis

open access: yesAdvanced Science, EarlyView.
γGC deficiency in ulcerative colitis drives macrophage ferroptosis‐mediated inflammation. Claw‐engaged microparticles armed with γGC (γGC‐MPs) enhance lesion targeting, promoting localized γGC release and tissue uptake. On the cover, Monkey King (Macrophages) was bound by the Immortal‐Binding Rope and subsequently sealed beneath the Five‐Fingered ...
Rong Wang   +10 more
wiley   +1 more source

Mitigation of SARS-CoV-2 by Using Transition Metal Nanozeolites and Quaternary Ammonium Compounds as Antiviral Agents in Suspensions and Soft Fabric Materials. [PDF]

open access: yesInt J Nanomedicine, 2023
Guerrero-Arguero I   +14 more
europepmc   +1 more source

Biomimetic Analysis of Neurotransmitters for Disease Diagnosis through Light‐Driven Nanozyme Sensor Array and Machine Learning

open access: yesAdvanced Science, EarlyView.
A novel photoresponsive nanozyme sensor array, combining metal‐organic frameworks (MOFs) with advanced machine learning algorithms, provides a breakthrough in rapid neurotransmitter detection and disease diagnostics. This sensor array is capable of accurately identifying neurotransmitter profiles associated with neurological disorders, offering ...
Kun Yu   +9 more
wiley   +1 more source

Ultra‐Low Hysteresis Under Large Deformation Enabled by Fast Chains Relaxation in Highly Competitive Dynamic Hydrogen Bond Networks

open access: yesAdvanced Science, EarlyView.
This study demonstrates that incorporating deep eutectic solvent (DES) components tunes the relaxation dynamics of strong hydrogen bonds between polymer segments, rendering them mechanically “invisible” during service conditions (low hysteresis: <3%).
Shuaijun Guo   +10 more
wiley   +1 more source

Synthesis and Antimicrobial Activity of 4-S-Methyl-1,3,4-Oxadiazole Derivatives of Some Natural Amino Acids Bearing Secondary Quaternary Ammonium Salt Moieties

open access: yesOrbital: The Electronic Journal of Chemistry, 2018
Secondary quaternary ammonium salts (QAS) derived from three natural amino acids (L-Leucine, L-Phenylalanine and L-Methionine) bearing 1,3,4-oxadiazole and acetic acid moieties have been synthesized and characterized by IR, 1H and 13C NMR.
Daoudi Sofiane   +3 more
doaj  

Evaluation of the inhibitory efficacy of quaternary ammonium compounds on in vitro growth of Theileria equi parasite in MASP culture. [PDF]

open access: yesInt J Parasitol Drugs Drug Resist, 2022
Suthar A   +5 more
europepmc   +1 more source

Nanomaterials Trigger Functional Anti‐Tumoral Responses in Primary Human Immune Cells

open access: yesAdvanced Science, EarlyView.
Nanoparticles are used to improve immunomodulatory therapies, but the impact of drug‐free nanomaterials on the immune system remains unknown. Screening common biomedical nanoparticles (NPs) reveals that PLGA NPs enhanced NK cell anti‐tumoral activity and transcriptional activation in human NK and pan T cells.
Vincent Mittelheisser   +20 more
wiley   +1 more source

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