Results 291 to 300 of about 70,527 (351)

Click‐Functionalized Cyanine Fluorogenic Dimers for Improved Detection of GPCRs: Application to Imaging of ApelinR in Living Cells

open access: yesChemistry – A European Journal, EarlyView.
A click‐mediated functionalization of a cyanine 5.5 bearing a terminal alkyne gave a rapid access to a library of ten new cyanine dyes and their corresponding dimers. A structure‐interaction relationship study led to the identification of an optimal dimer which was conjugated to the apelin‐17 ligand and enabled imaging of ApelinR under no‐wash ...
Océane Florès   +10 more
wiley   +1 more source

Conformational Switch in the Alpha‐Synuclein C‐Terminal Domain Directs Its Fibril Polymorphs

open access: yesChemistry – A European Journal, EarlyView.
The conformational state of the C‐terminal domain determines the fibril morphology of full‐length wild‐type alpha‐synuclein: high C‐terminus flexibility promotes twisted fibrils, while partial C‐terminal folding drives the assembly of rod‐like fibrils.
Cesar Aguirre   +25 more
wiley   +1 more source

Comprehensive Analysis of Crystalline Hydrophobic Alkylated Poly(ethyleneimine)s

open access: yesChemistry – A European Journal, EarlyView.
Alkylation of polyethyleneimine (PEI) induces crystalline hydrophobic domains, critical for CO₂‐mediated desalination. Structural evolution during acid/base treatment and ion exchange is revealed by PXRD, SAXS, and inelastic neutron scattering. Findings highlight reversible domain disruption and nanostructure formation, enabling recyclable polymer ...
Anand Sharadha‐Ravi Ayyar   +7 more
wiley   +1 more source

Recent Advances in Polyoxometalate‒Metal Nanocluster Hybrids

open access: yesChemistry – A European Journal, EarlyView.
POMs are gaining attention in metal nanocluster synthesis for their ability to impart unique structural and functional roles. This review highlights recent advances in POM–metal nanocluster hybrids, categorized as follows: (a) hybrids of POMs and metal nanoclusters stabilized by organic ligands, (b) metal nanoclusters stabilized by POMs as ligands, and
Kentaro Yonesato   +3 more
wiley   +1 more source

Copper‐Catalyzed Regioselective Meta C─H Bond Olefination of Anilides

open access: yesChemistry – A European Journal, Volume 31, Issue 31, June 3, 2025.
A Copper‐catalyzed meta C─H olefination of pivanilides with β‐styrenyl and β‐alkyl‐alkenyl iodonium salts was achieved using a weakly coordinated directing group (DG). The involvement of a Heck‐like four‐membered transition state was plausibly critical in ensuring the challenging meta selectivity.
Javid Rzayev   +2 more
wiley   +1 more source

Recent Advances in Detergent Chemistry and Handling Support Membrane Protein Analysis Including Lipid Interactions

open access: yesChemistry – A European Journal, EarlyView.
Detergent design parameters determine experimental successes in membrane protein research. Recent progresses in detergent chemistry are reviewed to promote the top‐down design of non‐ionic detergents for the purification and analysis of intact membrane proteins, including lipid interactions.
Katharina Alker   +2 more
wiley   +1 more source

Novel Para‐Phenylenediamine‐Based Derivatives as Receptor Tyrosine Kinase‐like Orphan Receptor 1 (ROR1) Inhibitors: An In Vitro Preliminary Characterization

open access: yesChemMedChem, EarlyView.
ROR1 represents a promising target for the development of novel antiproliferative compounds, giving its high expression in different cancer cell lines. The present study describes the workflow leading to the design, synthesis, and characterization of a series of para‐phenylenediamine‐based compounds able to interact with the target kinase, inhibiting ...
Gerardina Smaldone   +17 more
wiley   +1 more source

Antibacterial Activity of Textiles Functionalized with SilverSil

open access: yesChemNanoMat, EarlyView.
Cotton fabrics functionalized with SilverSil xerogel dispersed in eco‐friendly, water‐repellent coatings using the rod‐coating method show significant antibacterial activity against Staphylococcus aureus and Escherichia coli, reducing growth by 90.1% and 99%, respectively.
Giovanna Li Petri   +6 more
wiley   +1 more source

Determination of Quaternary Ammonium Compounds

Journal of Pharmaceutical Sciences, 1961
Abstract The official potassium ferricyanide assays of quaternary ammonium, preparations can be modified to include a potentiometric titration with silver nitrate instead of the suggested iodometric method for the determination of the excess ferricyanide. Sodium nitrite interferes with the ferricyanide assay methods.
John J. Hefferren, Carol L. Dietz
openaire   +3 more sources

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