Results 71 to 80 of about 72,446 (353)

Reactive trityl derivatives: stabilised carbocation mass-tags for life sciences applications [PDF]

, 2008
The rational design of novel triarylmethyl (trityl)-based mass tags (MT) for mass-spectrometric (MS) applications is described. We propose a "pKR+ rule" to correlate the stability of trityl carbocations with their MS performance: trityls with higher pKR+
Astakhova, Irina Kira, Astakhova, Irina V., Bernad, Pablo L., Khan, Safraz, Korshun, Vladimir A., Malakhov, Andrei D., Patel, Kaajal, Prokhorenko, Igor A., Shahgholi, Mona, Shchepinov, Mikhail S., Shmanai, Vadim V., Skorobogatyi, Mikhail V., Southern, Edwin M., Stepanova, Irina A., Ustinov, Alexey V.   +14 more
core   +2 more sources

Advanced Cellulose‐Based Gels for Wearable Physiological Monitoring: From Fiber Modification to Application Optimization

Advanced Functional Materials, EarlyView.
This review discusses cellulose‐based hydrogels technology, analyzes their application progress in physiological signal monitoring, and explores the effects of pretreatment, crosslinking, and molding methods on gel performance, to provide valuable insights into the efficient utilization of plant fibers and the environmentally friendly development of ...
Zhiming Wang, Jinxuan Jiang, Kexin Wei, Xiaojian Zhou, Muhammad Wakil Shahzad, Yifan Li, Xuehua Zhang, Ben Bin Xu, Shengbo Ge   +8 more
wiley   +1 more source

Synthesis of Methacrylate Monomers with Antibacterial Effects Against S. Mutans

Molecules, 2011
A series of polymerizable quaternary ammonium compounds were synthesized with the aim of using them as immobilized antibacterial agents in methacrylate dental composites, and their structures were characterized by FT-IR, 1H-NMR, and 13C-NMR analysis ...
Jingwei He, Monica Österblad, Pekka K. Vallittu, Lippo V. J. Lassila, Eva Söderling   +4 more
doaj   +1 more source

From ab initio quantum mechanics to molecular neurobiology: A cation-pi binding site in the nicotinic receptor [PDF]

, 1998
The nicotinic acetylcholine receptor is the prototype ligand-gated ion channel. A number of aromatic amino acids have been identified as contributing to the agonist binding site, suggesting that cation-pi interactions may be involved in binding the ...
Dougherty, Dennis A., Gallivan, Justin P., Lester, Henry A., Li, Lintong, Zhang, Yinong, Zhong, Wenge   +5 more
core  

Synthesis, Binding and Antiviral Properties of Potent Core-Extended Naphthalene Diimides Targeting the HIV-1 Long Terminal Repeat Promoter G-Quadruplexes [PDF]

, 2015
We have previously reported that stabilization of the G-quadruplex structures in the HIV-1 long terminal repeat (LTR) promoter suppresses viral transcription.
Botti, Silvia, Butovskaya, Elena, Doria, Filippo, Frasson, Ilaria, Freccero, Mauro, Grande, Vincenzo, Lago, Sara, Nadai, Matteo, Perrone, Rosalba, Richter, Sara, Scalabrin, Matteo   +10 more
core   +1 more source

Development of Substrate‐Independent Antifouling and Bactericidal Surfaces Using Visible Light Cross‐Linked Hydrogel Coatings for Biomedical Applications

Advanced Healthcare Materials, EarlyView.
A new antifouling, antithrombogenic, and bactericidal hydrogel coating method is developed for implantable medical devices. The hydrogel coating can be easily formed by visible‐light crosslinking and is universally applicable to all substrates, ranging from polymers to metals.
Soonjong Roh, Se Youn Jang, Youngmee Jung, Kangwon Lee, Jin Yoo   +4 more
wiley   +1 more source

Synthesis, Purification and Characterization of Polymerizable Multifunctional Quaternary Ammonium Compounds

Molecules, 2019
Methacrylate analogs of quaternary ammonium salts functionalized with carboxylic (AMadh1 68.8% yield, AMadh2 53.2% yield) and methoxysilane (AMsil1 94.8% yield, AMsil2 36.0% yield) groups were synthesized via Menschutkin reaction.
Ugochukwu C. Okeke, Chad R. Snyder, Stanislav A. Frukhtbeyn   +2 more
doaj   +1 more source

Photoactivatable drugs for nicotinic optopharmacology [PDF]

, 2018
Photoactivatable pharmacological agents have revolutionized neuroscience, but the palette of available compounds is limited. We describe a general method for caging tertiary amines by using a stable quaternary ammonium linkage that elicits a red shift in
A Nadler, AM Sarker, Anis Contractor, C Herbivo, C Xu, Can Peng, David L Wokosin, EJ Petersson, GC Ellis-Davies, Guiqing Zhao, H Taniguchi, Henry A Lester, HJ Motulsky, J Michael McIntosh, J Mütze, J Ren, J Rossi, J Schaal, JB Grimm, JB Grimm, John J Macklin, John J Marshall, Kyle R Gee, L Azam, L Azam, L Khiroug, L Madisen, Luke D Lavis, M Matsuzaki, M Matsuzaki, Matthew C Arvin, MJ Davis, N Asad, Nicholas M Bannon, NS Makarov, O Filevich, PY Shih, PY Shih, R Salas, R Zhao-Shea, Ryan M Drenan, Sambashiva Banala, SE Engle, ST McCarron, T Furuta, TA Pologruto, TW Chen, V Hagen, V Hagen, V Parikh, Veronica J Kim, VR Shembekar, Xiao-Tao Jin, Yevgenia Kozorovitskiy, Yong Wang   +54 more
core   +1 more source

Soft Nanocarriers as Antimicrobial Co‐Delivery Systems to Combat Resistant Infections

Advanced Healthcare Materials, EarlyView.
Soft nanocarrier‐based co‐delivery systems present a versatile and promising platform for combating antimicrobial resistance (AMR) by enabling spatiotemporally controlled, pathogen‐specific drug release. Their tunable physicochemical properties allow for the co‐encapsulation of synergistic antimicrobial agents, optimization of drug ratios, and surface ...
Anamarija Nikoletic, Evangelos Natsaridis, Timon Flathmann, Daiane P. C. Quadros, Nubia Gogniat, Oya Tagit   +5 more
wiley   +1 more source

Genome-Wide Transposon Screen of a Pseudomonas syringae mexB Mutant Reveals the Substrates of Efflux Transporters. [PDF]

, 2019
Bacteria express numerous efflux transporters that confer resistance to diverse toxicants present in their environment. Due to a high level of functional redundancy of these transporters, it is difficult to identify those that are of most importance in ...
Deutschbauer, Adam M, Helmann, Tyler C, Lam, Jennifer, Lindow, Steven E, Ongsarte, Caitlin L   +4 more
core   +1 more source