Results 21 to 30 of about 18,101 (260)

(2S,NS)-N-Allyl-N-benzyl-1-hydroxy-3-(4-hydroxyphenyl)-N-methylpropan-2-aminium bromide

Acta Crystallographica Section E, 2008
The title compound, C20H26NO2+·Br−, is an N-chiral quaternary ammonium salt synthesized from (2S*)-N-benzyl-N-methyltyrosine methyl ester. The dihedral angle between the phenyl ring and the benzene ring is 11.61 (19)°.
Hua-Fang Wu, Ying-Gang Luo, Kai-Bei Yu, Guo-Lin Zhang, Xin-Fu Pan   +4 more
doaj   +1 more source

Effective disinfecting of negative pressure pipelines of DCUs reduces the risk of cross infection in dental care

Journal of Oral Microbiology
Objectives Microbial contamination of various accessory parts of the dental chair units (DCUs) is an essential source of cross infection, while the accessories of the crucial suction function are usually overlooked.
Xuerong Lv, Ke Yan, Xiang Han, Feiyang Wang, Yuzhuo Ma, Shougang Zhang, Xiaoqian Wang   +6 more
doaj   +1 more source

Two Highly Effective Phase-Transfer Catalysts for the Enantioselective Synthesis of ?-Amino Acid Derivatives

CHIMIA, 2007
In this paper we review our recent studies into the phase-transfer catalysed asymmetric alkylation of glycine imines using quaternary ammonium salt catalysts derived from dihydrocinchonidine and ?-methylnaphthylamine.
Barry Lygo, Douglas J. Beaumont
doaj   +1 more source

A Remarkably Efficient Phase-Transfer Catalyzed Amination of α-Bromo-α, β-Unsaturated Ketones in Water

Heteroatom Chemistry, 2021
Tandem conjugate addition–alkylation reaction of various amines with α-bromo-α, β-unsaturated ketones resulted in near-quantitative conversions into the corresponding aziridines when the reaction was carried out in the presence of 10 mol% of phase ...
Alemayehu Mekonnen, Alemu Tesfaye
doaj   +1 more source

Curare-like Action of Polymethylene bis-Quaternary Ammonium Salts [PDF]

Nature, 1948
H.R. (Raymond) Ing was a chemist who developed a unique understanding of pharmacology, which arose from working on alkaloid chemistry. To the chemist he is Ing of the Ing and Manske reaction (for the preparation of primary amines) and responsible for working out the structure of the alkaloid cytisine.
R B, BARLOW, H R, ING
openaire   +5 more sources

Synthesis and Catalytic Activity of Bifunctional Phase-Transfer Organocatalysts Based on Camphor

Molecules, 2023
Ten novel bifunctional quaternary ammonium salt phase-transfer organocatalysts were synthesized in four steps from (+)-camphor-derived 1,3-diamines. These quaternary ammonium salts contained either (thio)urea or squaramide hydrogen bond donor groups in ...
Luka Ciber, Franc Požgan, Helena Brodnik, Bogdan Štefane, Jurij Svete, Mario Waser, Uroš Grošelj   +6 more
doaj   +1 more source

Antifungal activity of gemini quaternary ammonium salts

Microbiological Research, 2013
A series of gemini quaternary ammonium chlorides and bromides with various alkyl chain and spacer lengths was synthesized. The most active compounds against fungi were chlorides with 10 carbon atoms within the hydrophobic chain. Among these compounds were few with no hemolytic activity at minimal inhibitory concentrations.
Obłąk, Ewa, Piecuch, Agata, Krasowska, Anna, Łuczyński, Jacek   +3 more
openaire   +2 more sources

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Synthesis, characterization, and bioactivity of rosin quaternary ammonium salt derivatives [PDF]

BioResources, 2013
Two series of rosin quaternary ammonium salts (QAS) were synthesized using the same path. The structure of the target products was characterized by HPLC, MS, IR, and 1HNMR, and the bioactivity was determined by filter paper method using Trametes ...
Tao Liang, Yuanyuan Zhang, Shujun Li, Thi Thanh Hien Nguyen   +3 more
doaj  

Combinatorial Synthesis of Next Generation Water‐Soluble Quaternized N‐Halamine Oligomers with Long‐Lasting Antiviral Properties

Advanced Functional Materials, EarlyView.
A combinatorial library of dual‐functional antiviral oligomers incorporating N‐halamine and quaternary ammonium functionalities is developed for long‐lasting antiviral activity. The lead materials exhibit rapid and durable antiviral activity against SARS‐CoV‐2 variants and influenza H1N1, with 4 to 5 log reduction in viral copies at 5 mg mL−1 ...
Eid Nassar‐Marjiya, Konda Reddy Kunduru, Krishanu Ghosal, Luna Rizik, Nofar Atari, Mahran Daifa, Neta Kutner, Bassma Khamaisi, Qi Wu, Simran Jindal, Merna Shaheen‐Mualim, Ranabir Majumder, Mahitosh Mandal, Michal Mandelboim, Shady Farah   +14 more
wiley   +1 more source