Results 81 to 90 of about 20,590 (293)

CD177 Deficiency Defines a Stable Subtype of Human Neutrophil Granulocytes with Tumor Promoting Activity

Advanced Science, EarlyView.
Human neutrophils exist as two epigenetically imprinted subtypes defined by stable CD177 expression or absence — a ratio that persists across time, circadian rhythms, and inflammation. CD177− neutrophils display a distinct molecular landscape enriched in arginase 1 and lipid metabolism markers, accumulate in head‐and‐neck tumors, and associate with ...
Marcel Jung, Alexander Beer, Susmita Ghosh, Ekaterina Pylaeva, Belal Alshaar, Tobias Tertel, Nils Bastian Leimkühler, Thomas Schroeder, Janine Gronewold, Nina Hagemann, Ayan Mohamud Yusuf, Benedikt Frank, Yiqiao Zhang, Dennis Nagel, Kim Schloeßer, Laura Karsch, Emily Hedtfeld, Sabrina Lohmann, Kathrin Blank, Andreas Kraus, Max Krumbein, Nastassia Kabankova, Hongxiao Wang, Almke Bader, Mathis Richter, Fengjun Zhang, Raphael Chevre, Bernd Giebel, Stephan Lang, Anika Grüneboom, Daniela Maier‐Begandt, Anja Hasenberg, Oliver Soehnlein, Hans Christian Reinhardt, Sven Heiles, Jianxu Chen, Jadwiga Jablonska, Albert Sickmann, Dirk M. Hermann, Matthias Gunzer   +39 more
wiley   +1 more source

Microalbuminuria sensitive near‐infrared AIE probe for point‐of‐care evaluating kidney diseases

Aggregate
Urinary microalbumin (mALB) serves as an exceptionally sensitive indicator for the early detection of kidney damage, playing a pivotal role in identifying chronic renal failure and kidney lesions in individuals.
Zhirong Zhu, Xiaoyan Chen, Hongze Liao, Li Li, Haojian Yang, Qi Wang, Wei‐Hong Zhu   +6 more
doaj   +1 more source

Linear Synthesis of 10-Hydroxy-N,N-dimethyl-N-((3-(tosyloxy)pyridin-2-yl)methyl)decan-1-aminium Bromide

Molbank
In 2019, carbamates derived from 3-hydroxypyridine were classified as nerve agents and subsequently included in the Annex on Chemicals by the Conference of the States Parties.
Václav Hron, Martin Urban, Tomáš Tobrman   +2 more
doaj   +1 more source

Scalable Synthesis of Salt-free Quaternary Ammonium Carboxylate Catanionic Surfactants

Acta Chimica Slovenica, 2020
Surfactants in commercial products commonly contain catanionic mixtures thus many studies of aqueous surfactant mixtures have been carried out. However, hardly any studies have been dedicated to pure catanionic surfactants often termed salt-free ...
Žiga Medoš, Miha Virant, Urša Štanfel, Boštjan Žener, Janez Košmrlj, Marija Bešter-Rogač   +5 more
doaj   +1 more source

A Pathology‐Instructed Theranostic Platform with Mechanoadaptive and ROS‐Powered Nanobreathing Functions for Precision Myocardial Repair

Advanced Science, EarlyView.
We developed a pH responsive theranostic serum albumin hydrogel named BST, functionalized with MRI and CT probes and loaded with mitochondria targeted CAT‐SOD nanogels, that rapidly self repairs and mechanically stabilizes the infarcted myocardium, releases therapeutic nanogels and albumin under hypoxia induced acidosis to clear mitochondrial ROS ...
Zheng Luo, Cui Yang, Liuzhou Mao, Panqin Ma, Chiyu Jia, Karen Yuanting Tang, Xian Jun Loh, Yun‐Long Wu   +7 more
wiley   +1 more source

Solution-Processed White Organic Light-Emitting Diodes with Enhanced Efficiency by Using Quaternary Ammonium Salt Doped Conjugated Polyelectrolyte [PDF]

, 2016
Solution-processed white organic light emitting diodes (WOLEDs) with quaternary ammonium salt doped water/alcohol soluble conjugated polyelectrolyte, poly­[(9,9-bis­(3′-((N,N-dimethyl)-N-ethylammonium)-propyl)-2,7-fluorene)-alt-2,7-(9,9-dioctylfluoren ...
Yuan Tian (225002), Xinjun Xu (1449574), Chuang Yao (1793389), Jinshan Wang (1614487), Lidong Li (1449565)   +4 more
core   +1 more source

(E)-8-(4-(4-(Diphenylamino)styryl)phenoxy)-N,N,N-trimethyloctan-1-aminium Bromide

Molbank
Structural optimization integrating triphenylamine and quaternary ammonium salt-based antimicrobial peptide mimics has yielded novel theranostic hybrid molecules.
Saiya Yang, Ya-Na Wang, Yuyang Ma, Ruirui Li, Maxwell Ampomah-Wireko, Cedric Dzidzor Kodjo Amengor, En Zhang, Yi-Hong Zhao   +7 more
doaj   +1 more source

PRMT5‐Dependent Stabilization of VPS34 Orchestrates Copper Trafficking to Shield Cancer Cells from Cuproptosis and Radiotherapy

Advanced Science, EarlyView.
Radioresistance arises partly from tumor cells evading cuproptosis via unknown defenses. This study reveals that the PRMT5‐VPS34 axis acts as a radiation‐activated anticuproptotic mechanism: PRMT5 methylates VPS34 at Arg174, recruiting USP10 to remove K48‐linked ubiquitination and prevent degradation.
Wei Chen, Ming‐Ying Xiao, Lan‐Lan Guo, Hao‐Yue Hu, Sui‐Xian Zhang, Bai‐Qiang Dong, Chen‐Fei Wu, Xia‐Hang Huang, Li Li, Run‐Zhe Chen, Yuan‐Yang Huang, Ying Jin, Hai Song, Ying Wang, Qi‐Wen Li, Ming Chen, Xuan Li, Yuan‐Yuan Chen   +17 more
wiley   +1 more source

Helvetica Chimica Acta / Chiral Quaternary Ammonium Salt-Catalyzed Enantioselective Addition Reactions of Hydantoins [PDF]

We herein report a protocol for the asymmetric 1,4-addition of hydantoins to various Michael acceptors by utilizing Cinchona alkaloid-based chiral quaternary ammonium salt catalysts.
Prameshuber, Lucas, Röser, Katharina, Jahangir, Sajid, Mallojjala, Sharath Chandra, Hirschi, Jennifer S., Waser, Mario   +5 more
core   +1 more source

An antistatic agent based on polyionic liquid applied to nylon 6

Green Chemical Engineering
In order to improve the electrical conductivity of nylon 6 (PA6) and avoid misfires and explosions caused by static charge accumulation, a quaternary ammonium salt polyionic liquid (PIL) antistatic agent was synthesized in this paper.
Shuangchan Fu, Yinghao Yu, Feng Wang, Jing Li, Zhiqi Cai   +4 more
doaj   +1 more source