Results 41 to 50 of about 3,901,558 (191)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Color face recognition using quaternion PCA [PDF]
, 2011 Recently, biometric systems have attracted the attention of both academic and industrial communities. Advances in hardware and software technologies have paved the way to such growing interest.
Jaha, Emad Sami, Lahouari, Ghouti
core +2 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Totally Real Submanifolds in a Quaternion Projective Space
Tokyo Journal of Mathematics, 1996 Let \(M\) be an \(n\)-dimensional compact totally real minimal submanifold in the quaternionic projective space \(QP^n(c)\) of constant quaternionic sectional curvature \(c\). Denote by \(\rho\) the scalar curvature of \(M\), by \(\sigma\) the second fundamental form of \(M\), and by \(K_c\) and \(Q\) the functions assigning to each point \(p\in M ...
openaire +3 more sources
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
On submersion and immersion submanifolds of a quaternionic projective space [PDF]
Acta Universitatis Sapientiae, Mathematica, 2016 Abstract We study submanifolds of a quaternionic projective space, it is of great interest how to pull down some formulae deduced for submanifolds of a sphere to those for submanifolds of a quaternionic projective space.
Abedi Esmail, Nazari Zahra
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
On Connectedness of the Space of Harmonic 2-Spheres in Quaternionic Projective Spaces
Tokyo Journal of Mathematics, 1994 Let \(\mathbb{H} P^ n(c)\) be an \(n\)-dimensional quaternionic projective space with the maximum \(c\) of the sectional curvatures. It is known that there are two natural twistor spaces \({\mathcal T}_ n\) and \(\mathbb{C} P^{2n +1}\) over \(\mathbb{H} P^ n\). A harmonic map \(\varphi : \Sigma \to\mathbb{H} P^ n(c)\) is called strongly isotropic (resp.
openaire +3 more sources
Isospin particle systems on quaternionic projective spaces [PDF]
Physical Review D, 2013 8 pages, PACS numbers: 03.65-w, 02.30.Ik, 1 reference ...
Stefano Bellucci +3 more
openaire +2 more sources