Results 131 to 140 of about 6,678 (298)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Generalized Pauli Fibonacci Polynomial Quaternions
AxiomsSince Hamilton proposed quaternions as a system of numbers that does not satisfy the ordinary commutative rule of multiplication, quaternion algebras have played an important role in many mathematical and physical studies.
Bahadır Yılmaz +2 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Geometric structures based on quaternions.
, 2010 A pair (V, G) is called geometric structure, where V is a vector space and G is a subgroup GL(V), which is a set of transmission matrices. In this thesis we classify structures, which are based on properties of quaternions.
Floderová, Hana
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
A Survey on Solving the Matrix Equation AXB = C with Applications
MathematicsThis survey provides a comprehensive overview of the solutions to the matrix equation AXB=C over real numbers, complex numbers, quaternions, dual quaternions, dual split quaternions, and dual generalized commutative quaternions, including various special
Qing-Wen Wang, Lv-Ming Xie, Zi-Han Gao
doaj +1 more source
SymmetrySymmetry transformations in crystallography are traditionally represented as equations and matrices, which can be suitable both for orthonormal and crystal reference systems. Quaternion representations, easily constructed for any orientations of symmetry operations, owing to the vector structure based on the direction of the rotation axes or of the ...
Andrzej Katrusiak, Stiv Llenga
openaire +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source