Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa+13 more
wiley +1 more source
Motion-BIDS: an extension to the brain imaging data structure to organize motion data for reproducible research. [PDF]
Jeung S+10 more
europepmc +1 more source
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki+11 more
wiley +1 more source
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley +1 more source
Learning-based 3D human kinematics estimation using behavioral constraints from activity classification. [PDF]
Kim D+8 more
europepmc +1 more source
Examination of a practical method to quantitatively evaluate the rolling over movement in a clinical setting. [PDF]
Yamanaka Y+3 more
europepmc +1 more source
Expansion of stereotactic work envelope using transformation matrices and geometric algebra for neurosurgery. [PDF]
Sharaf B+15 more
europepmc +1 more source
Subjective and Objective Assessment of the Preferred Rotational Cervical Spine Position in Infants with an Upper Cervical Spine Dysfunction: A Cross-Sectional Study. [PDF]
Langenfeld A+6 more
europepmc +1 more source
Online Handwriting Recognition Method with a Non-Inertial Reference Frame Based on the Measurement of Linear Accelerations and Differential Geometry: An Alternative to Quaternions. [PDF]
Abarca Jiménez GS+5 more
europepmc +1 more source