Results 121 to 130 of about 9,262 (286)

Endosomal Escape of siRNA Polyplexes: A Molecular Dynamics Perspective on Underlying Mechanisms

Advanced Functional Materials, EarlyView.
Molecular dynamics simulations reveal distinct endosomal escape mechanisms of siRNA nanoparticles, ranging from electrostatic membrane attachment to hydrophobic membrane fusion. Hydrophobic residues and anionic endosomal lipids emerge as key determinants of membrane disruption, linking molecular interactions to experimental delivery performance and ...
Katharina M. Steinegger, Min Jiang, Florian Belger, Fabian Link, Benjamin Winkeljann, Olivia M. Merkel   +5 more
wiley   +1 more source

Protease‐Activated Theranostic Nanomedicine for Endometriosis Treatment

Advanced Functional Materials, EarlyView.
Endometriosis is a chronic gynecological disorder that affects a substantial proportion of reproductive‐aged women. In this study, we identify aberrant overexpression of matrix metalloproteinase‐9 (MMP‐9) in endometriotic lesions and develop a novel multifunctional nanomedicine that integrates MMP‐9‐targeted therapy, ratiometric photoacoustic (PA ...
Panangattukara Prabhakaran Praveen Kumar, Tae Hoon Kim, Hossein Hosseinirad, Maggie Lee, HyeJoo An, Bruce A. Lessey, Daniel Hanavi, Jung‐Ho Shin, Jae‐Wook Jeong, Taeho Kim   +9 more
wiley   +1 more source

Development of quenching and partitioning steels (Q&P)

(English) The automotive industry is constantly seeking to improve the performance of the car and at the same time reduce CO2 emissions into the environment, which can be achieved among other solutions through the use of advanced high-strength steels (AHSS) that help reduce the weight of the car and keep the safety of the passengers.
openaire   +2 more sources

A Critical Review on Quenching and Partitioning on Commercial Steels

, 2017
To increase the ductility and hardness we mainly focus in our experiment to convert BCC structure into FCC from BCT structure and avoid formation of BCC structure after cooling which is called as formability. Here atoms are in BCC structure when we austempered energy is absorbed by carbon atom and bonds with another matrix and forms FCC structure ...
Kumar, Govind Sai, Reddy, Birudala Raga Harshith, Kumar, M Bharath, Vishal, Pittala   +3 more
openaire   +1 more source

Material Coupling in Hybrid Neuromorphic Devices: From Fundamentals to System‐Level Applications

Advanced Functional Materials, EarlyView.
Hybrid neuromorphic devices utilize heterointerfaces between emerging semiconductors, where charge transfer and trapping, ion or defect modulation, and photogating are translated into synaptic functions. This paper discusses coupling strategies that tailor interfacial electronic and ionic properties in organic semiconductors, metal oxides, two ...
Minsu So, Sunwoo Jeong, Youngmin Han, Fabrizio Torricelli, Hocheon Yoo, Junhwan Choi   +5 more
wiley   +1 more source

Biomimetic Hybrid‐Membrane Nanoreactor for Deep‐Seated Photodynamic Immunotherapy of Hepatocellular Carcinoma via Dual Catalysis‐Enhanced ROS Amplification and cGAS‐STING Activation

Advanced Functional Materials, EarlyView.
UCNP@MnOx‐Hyp@HRM (UMHM) enables tumor targeting and accumulation. Under 808 nm NIR irradiation, PDT/CDT synergistically triggers ICD and cGAS–STING immunity for deep hepatocellular carcinoma therapy. ABSTRACT Photodynamic therapy (PDT) is promising against hepatocellular carcinoma (HCC).
Wen Li, Jianzhang Luo, Pei Lu, Dongqing Liu, Huijun Yi, Xiaoyuan Yi, Bixia Chi, Wen Chen, Qingyu Zeng, Feifei He, Liyan Wang   +10 more
wiley   +1 more source

Highly Efficient and Stable Roll‐to‐Roll Coated Perovskite Solar Cells Enabled by Antisolvent Vapor‐Assisted Crystallization

Advanced Functional Materials, EarlyView.
Antisolvent Vapour‐Assisted Crystallization (AVAC) enables controlled perovskite crystallization through precisely metered antisolvent vapour, eliminating liquid antisolvent waste. Compatible with roll‐to‐roll (R2R) slot‐die coating, AVAC produces uniform, pinhole‐free films with enlarged grains, delivering efficiencies of 18.3% for R2R fabricated ...
Narendra Pai, Andrew D. Scully, Yogesh Gulia, Aaron Seeber, Jueng‐Eun Kim, Luke J. Sutherland, Doojin Vak, Jacob Yin, Mark Greaves, Malisja de Vries, Mei Gao, Dechan Angmo   +11 more
wiley   +1 more source

QUENCHING AND PARTITIONING OF AISI 4340 STEEL [PDF]

, 2017
Quenching and Partitioning (Q & P), an innovative heat treatment process was developed by J. G. Speer in 2003 to produce third generation high strength steels with improved toughness for making chassis of high speed cars.
Muhammad Haseeb Hassan; IQTM, University of the Punjab, Lahore, Aqil Inam; DMME, University of the Punjab, Lahore, Muhammad Rizwan; DMME, University of the Punjab, Lahore, Mubushar Nawaz; DMME, University of the Punjab, Lahore, Muhammad Ishtiaq; DMME, University of the Punjab, Lahore, Arslan Hafeez; DMME, University of the Punjab, Lahore   +5 more
core   +2 more sources

Formation of a Heterophase Structure in Low-Alloyed Steel by Means of Application of Innovative Technology of Heat Treatment by ‘Quenching and Partitioning’

, 2018
В статье описаны фазово-структурный состав и механические свойства низколегированной стали 60С2ХФА, подвергнутой обработке «Quenching and Partitioning» (Q-n-P).У статті описано фазово-структурний склад і механічні властивості низьколеґованої сталі ...
Ефременко, А.В., Помазков, М.В., Гаврилова, В.Г., Кусса, Р.А., Зурнаджи, В.И., Кудин, В.В., Ефременко, В.Г.   +6 more
core   +1 more source

Atom‐Efficient Cerium‐Based Molecular Cages as Biocompatible Reactive Oxygen Scavengers

Advanced Healthcare Materials, EarlyView.
Discrete mixed‐valent cerium molecular cages organize accessible redox centers within confined coordination environments and scavenge superoxide, hydrogen peroxide, and hydroxyl radicals. Encapsulation of the lead cage in an ROS‐responsive DTP nanoplatform enables lesion‐associated delivery, attenuates macrophage oxidative stress and inflammation, and ...
Chao Li, Chunbai Xiang, Ye Xu, Yu Liu, Keze Hong, Fanchu Zeng, Gelin Xu, Zhao‐Xi Wang, Jonathan L. Sessler, Ping Gong   +9 more
wiley   +1 more source