Results 151 to 160 of about 121,244 (316)

Single-molecule fluorescence studies of Protein Folding and Molecular Chaperones [PDF]

, 2011
Folding of newly synthesized proteins is an essential part of protein biosynthesis and misfolding can result in protein aggregation which can also lead to several severe diseases.
Sikor, Martin
core  

Coaxial Melt Electrowriting

Advanced Materials Technologies, EarlyView.
Coaxial melt electrowriting is established to produce dual‐property microfibers with diameters spanning 1.6–29.2 µm. Stable coaxial laminar flow is preserved under electrohydrodynamic thinning, enabling controlled binary and gradient material switching within individual continuous fibers.
Patrick C. Hall, D. Iman von Briesen, Maya Kasteleiner, Gabriela M. Bailey, Diana Ostojich, Harrison W. Reid, Andre Olarra, Benjamín J. Alemán, Simon Luposchainsky, Biranche Tandon, Ramesh Jasti, Paul D. Dalton   +11 more
wiley   +1 more source

Mitigating Efficiency Roll‐Off in Phosphor‐Sensitized Fluorescence OLEDs via Molecular Polarity‐Based Benzofuropyridine Host Engineering

Advanced Optical Materials, EarlyView.
Positional isomerism in dibenzofuran‐based n‐type hosts modulates molecular polarity, charge‐transport balance, and emissive‐layer packing. The higher‐polarity BFPDB‐2 host facilitates efficient energy funneling, reduced aggregation, and preferential dipole orientation, leading to phosphor‐sensitized fluorescence OLEDs with enhanced external quantum ...
Nargis Ali, Xuyao Song, Yun‐Hi Kim, Min Chul Suh   +3 more
wiley   +1 more source

A Proline‐Integrated Donor–Acceptor Fluorophore: Water‐Vapor‐Responsive Mechanochromic Luminescence and Latent Fingerprint Visualization

Advanced Optical Materials, EarlyView.
A proline‐integrated donor–acceptor fluorophore enables multifunctional luminescence through rational molecular design. Water‐vapor‐responsive mechanochromic luminescence (MCL) with circularly polarized luminescence (CPL) switching and efficient visualization of latent fingerprints (LFPs) are realized from this single small organic molecule.
Hao Chen, Kazuki Kato, Yoshitane Imai, Suguru Ito   +3 more
wiley   +1 more source

Neodymium‐Doped Nanocrystals for Sensing Cellular Temperature at the Nanoscale

Advanced Optical Materials, EarlyView.
Neodymium‐doped NaYF4 nanocrystals are engineered as bright, biocompatible nanothermometers for intracellular temperature mapping. Their ratiometric near‐infrared emission enables highly sensitive, nanoscale thermal readouts in living cells. Combined with gold nanostars for photothermal therapy, they reveal pronounced subcellular heating heterogeneity ...
Maria Bravo, Sandra Krzyzowska, Shelly Yang, Dingchen Wen, Jana Zielinski, Farsai Taemaitree, Samantha Zaman, Alastair Stewart, Susana Rocha, Paul Mulvaney, Hiroshi Uji‐i, Beatrice Fortuni, Sam Brooke, James Hutchison   +13 more
wiley   +1 more source

Bayesian‐Optimized Dual‐Mode Luminescence‐Based Optical Thermometry Enabled by Negative Thermal Expansion in Lu2(MoO4)3:Yb–Er–Tm Phosphor

Advanced Optical Materials, EarlyView.
A Bayesian optimization framework identifies the ideal composition for Lu2(MoO4)3:Yb–Er–Tm phosphors with minimal experimental trials. By leveraging the host's negative thermal expansion, the material achieves remarkable thermal quenching compensation.
Reiko Furukawa, Takuya Hasegawa, Tong Fang, Saneyuki Ohno, Tomoyo Goto, Yasushi Sato, Ayahisa Okawa, Shu Yin   +7 more
wiley   +1 more source

Information Transmission Strategies for Self‐Organized Robotic Aggregation

Advanced Robotics Research, EarlyView.
In this review, we discuss how information transmission influences the neighbor‐based self‐organized aggregation of swarm robots. We focus specifically on local interactions regarding information transfer and categorize previous studies based on the functions of the information exchanged.
Shu Leng, Zihan Li, Yifeng Shao, Jinhao Liu, Li Yu, Shuguang Li   +5 more
wiley   +1 more source

Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells

Advanced Science, EarlyView.
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia, William Y. Wang, Kyle A. Jacobs, Kairav Maniar, Daphne Lin, Evan H. Jarman, Daniel L. Matera, Kristen Loesel, Christopher D. Davidson, Harrison L. Hiraki, Xiaotian Tan, Eve H. Shikanov, Robert N. Kent, Carole Parent, Xudong Fan, Ariella Shikanov, Matthew L. Kutys, Brendon M. Baker   +17 more
wiley   +1 more source

Dual expression recombinase based (DERB) single vector system for high throughput screening and verification of protein interactions in living cells

, 2008
Identification of novel protein interactions and their mediators is fundamental in understanding cellular processes and is necessary for protein-targeted therapy.
Jian-Ping Lu, Laura Beatty, Jehonathan Pinthus, JianPing Lu, Jehonathan Pinthus   +4 more
core  

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source