Advanced Healthcare Materials, EarlyView.This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche +8 more
wiley +1 more source
Multifunctional kojic acid-tetrahydroisoquinoline hybrids: Synthesis, tyrosinase inhibition, and applications in the anti-browning of fresh-cut mushrooms. [PDF]
Curr Res Food SciLv M +7 more
europepmc +1 more source
A Biomimetic Buffering Hydrogel Scaffold for Long‐Term Culture of Patient‐Derived Tumor Organoids
Advanced Healthcare Materials, EarlyView.A biomimetic fibrous buffering hydrogel controls the local acidification at the tumoroid/hydrogel interface at the physiologically relevant level over 21‐day culture. The buffering effect promotes cancer cell proliferation in the tumoroids and supports the structural integrity and mechanical properties of the hydrogel scaffold over long‐term tumoroid ...
Elizaveta Gusarova +5 more
wiley +1 more source
Very simple and ultra-sensitive fluorescence resonance energy transfer aptasensor for turn-on C-reactive protein detection in biological matrices. [PDF]
Sci RepFathi Ganje Lou E +4 more
europepmc +1 more source
An Ultrapotent, Ultraeconomical, Antifreeze Polypeptide
Advanced Materials, EarlyView.Simple and inexpensive polypeptides composed of random copolymers of alanine and glutamic acid are effective antifreezes for applications in foods and biomedicine. The polypeptides, inspired by natural extremophile proteins, inhibit the growth of large ice crystals and prevent damage to sensitive biologics.
Thomas J. McPartlon +5 more
wiley +1 more source
Recent developments and future perspectives for photoresponsive-based gold nanoparticles (Au-NPs) and their biomaterial applications. [PDF]
RSC AdvRajasekar M, Sivakumar M.
europepmc +1 more source
Advanced Materials, Volume 37, Issue 13, April 2, 2025.Metal‐covalent organic frameworks (MCOFs) are novel porous materials that exhibit the advantages of covalent and metal‐organic frameworks. However, it is extremely difficult to resolve their atomic structure and better understand their structure‐properties relation. This work utilizes a synergistic combination of advanced microscopy, spectroscopic, and
Seán Hennessey +11 more
wiley +1 more source
Optical bio/chemical sensors for vitamin B<sub>12</sub> analysis in food and pharmaceuticals: state of the art, challenges, and future outlooks. [PDF]
Beilstein J NanotechnolGharibzahedi SMT, Altintas Z.
europepmc +1 more source