Results 51 to 60 of about 19,864 (256)

Long‐Lasting Auditory and Vestibular Recovery Following Gene Replacement Therapy in a Novel Usher Syndrome Type 1c Mouse Model

Advanced Science, EarlyView.
This study shows that gene replacement therapy using the AAV2/Anc80L65 virus can successfully restore hearing and balance in Ush1c knockout mice. The treatment leads to lasting improvements in both auditory and vestibular functions, highlighting its potential as a therapeutic approach for genetic hearing loss and vestibular disorders in humans ...
Weinan Du, Jun Huang, Aizhen Zhang, Fangfang Zhao, Tianwen Chen, Quinn M. McDermott, Tony Zheng, Haibo Wang, Rongli Zhang, Xiaolin Zhang, Jerome Allison, Hong Zhu, Wu Zhou, Qing Yin Zheng   +13 more
wiley   +1 more source

Desarrollo de un sistema de búsquedas en voz basadas en ejemplos [PDF]

, 2017
En la actualidad existen diversas técnicas para implementar un sistema de búsqueda en voz. En este TFG se describe el desarrollo de un sistema de búsqueda en voz basadas en ejemplos usando el método QbE - STD (Query-by-Example – Spoken Detection Term ...
Aguirre Villar, María Begoña
core  

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

Advanced Science, EarlyView.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao, Tian Shen, Shengda Cao, Ziyi Liu, Wendu Pang, Meixuan Li, Jingjing Liu, Wen Li, Yunhao Wu, Chengcheng Liu, Ming Xia, Xiaolong Fu, Cheng Cheng   +12 more
wiley   +1 more source

Post‐Translational Modifications in Cilia and Ciliopathies

Advanced Science, EarlyView.
This review synthesizes current understanding of post‐translational modifications (PTMs) in ciliary proteins and emphasizes their roles in ciliary formation, homeostasis, and signaling. This review also discusses the implication of PTM dysregulation in ciliopathies and explores therapeutic strategies targeting PTM‐modifying enzymes.
Jie Ran, Jun Zhou
wiley   +1 more source

From Waste to Wealth: A Review of Eutectic Molten Salt Method for Direct Regeneration of Spent Lithium‐Ion Battery

Advanced Science, EarlyView.
The main process of the eutectic molten salt method and the direct regeneration of Spent lithium (Li)‐ion batteries by the eutectic molten salt method have brought structural, performance, environmental, and economic benefits. Abstract The rapid growth of electric vehicles (EVs) has significantly increased the demand for lithium (Li)‐ion batteries ...
Junyi Wang, Zehua Qi, Qi Zhao, Kaimin Shih   +3 more
wiley   +1 more source

Towards Affordable Disclosure of Spoken Word Archives [PDF]

, 2008
This paper presents and discusses ongoing work aiming at affordable disclosure of real-world spoken word archives in general, and in particular of a collection of recorded interviews with Dutch survivors of World War II concentration camp Buchenwald ...
Heeren, W.F.L., Hiemstra, D., Huijbregts, M.A.H., Jong, F.M.G. de, Ordelman, R.J.F.   +4 more
core   +2 more sources

BiSbF2 Monolayer: A 2D Inversion‐Asymmetric Topological Insulator With Linearly Tunable Giant Spin‐Splitting and Bulk Gap

Advanced Electronic Materials, EarlyView.
The BiSbF2 monolayer is a 2D topological insulator with a large bandgap (252 meV) hosting topological edge states and giant valley‐contrasted spin‐splitting (478 meV). The sizable gap enables room‐temperature quantum spin Hall effects, while its coexisting topological and valleytronic features provide a versatile platform for exploring topological ...
Bin Geng, Hongli Xin, Xin Cui, Tielei Song, Zhifeng Liu   +4 more
wiley   +1 more source

Increasing sedentary time, minimum dietary energy requirements, and food security assessment

Applied Economic Perspectives and Policy, EarlyView.
Abstract We compute corrections for sedentary behavior in physical activity levels (PALs) and incorporate them along with corrections for over estimation of basal metabolic rates (BMRs) into threshold caloric intakes, known as minimum dietary energy requirements (MDERs).
Jacob Michels, Yacob Abrehe Zereyesus, John Beghin   +2 more
wiley   +1 more source

Multimedia information technology and the annotation of video [PDF]

, 2006
The state of the art in multimedia information technology has not progressed to the point where a single solution is available to meet all reasonable needs of documentalists and users of video archives.
Jong, F.M.G. de, Smeulders, A., Worring, M.   +2 more
core   +1 more source

What matters for agricultural trade? Assessing the role of trade deal provisions using machine learning

Applied Economic Perspectives and Policy, EarlyView.
Abstract This paper employs machine learning to determine which preferential trade agreement (PTA) provisions are relevant to agricultural trade patterns and the factors that may influence their adoption. Utilizing the three‐way gravity model, we apply plug‐in Lasso regularized regression to pinpoint predictive PTA provisions for agricultural trade ...
Stepan Gordeev, Jeremy Jelliffe, Dongin Kim, Sandro Steinbach   +3 more
wiley   +1 more source