Results 111 to 120 of about 635,069 (331)

Online Sorting via Searching and Selection

open access: yes, 2009
In this paper, we present a framework based on a simple data structure and parameterized algorithms for the problems of finding items in an unsorted list of linearly ordered items based on their rank (selection) or value (search).
Gupta, Ankur   +2 more
core   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

Mapping Object-Oriented Database Models Into RDF(S)

open access: yesIEEE Access, 2018
Resource description framework RDF and RDF schema (collectively called RDF(S)) are the normative languages to describe the Web resource information. How to construct RDF(S) from the existing data sources is becoming an important research issue.
Qiang Tong
doaj   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Investigation of the Uniformity of Gel Shrinkage by Imaging Tracer Particles Using X‐Ray Microtomography

open access: yesAdvanced Engineering Materials, EarlyView., 2023
A novel method for tracking structural changes in gels using widely accessible microcomputed tomography is presented and validated for various hydro‐, alco‐, and aerogels. The core idea of the method is to track positions of micrometer‐sized tracer particles entrapped in the gel and relate them to the density of the gel network.
Anja Hajnal   +3 more
wiley   +1 more source

Bridging Data Models in Health Care With a Novel Intermediate Query Format for Feasibility Queries: Mixed Methods Study

open access: yesJMIR Medical Informatics
BackgroundTo advance research with clinical data, it is essential to make access to the available data as fast and easy as possible for researchers, which is especially challenging for data from different source systems within and across institutions ...
Lorenz Rosenau   +5 more
doaj   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Improving the Search Mechanism for Unstructured Peer-to-Peer Networks Using the Statistical Matrix Form

open access: yesIEEE Access, 2015
In a traditional file search mechanism, such as flooding, a peer broadcasts a query to its neighbors through an unstructured peer-to-peer (P2P) network until the time-to-live decreases to zero.
Chia-Hung Lin   +2 more
doaj   +1 more source

Small modifier, big decision: switching to SUMO mode adds weight to cancer stemness in mammary tumors

open access: yesMolecular Oncology, EarlyView.
Inhibition of protein SUMOylation has been shown to block tumorigenesis; however, the specific mechanisms by which SUMOylation controls the tumor‐initiating capacities remain elusive. Li et al. describe the role of Etv1 SUMOylation in cancer stem cells using mouse models of mammary gland tumorigenesis.
Veronika Yevdokimova, Yannick D. Benoit
wiley   +1 more source

OPTIMISATION ANALYSIS OF TRANSACT-SQL QUERIES BASED ON INDEXES

open access: yesInformatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska, 2017
The article presents a discussion of the optimisation methods involving the modification of query syntax on the example of the use of indexes that served for the application of the methods in practice, and the presentation and analysis of the test ...
Dominika Hodun   +1 more
doaj   +1 more source

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