Results 101 to 110 of about 197,373 (301)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Learning to rank query expansion terms for COVID-19 scholarly search. [PDF]
J Biomed Inform, 2023 Khader A, Ensan F.
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
RbQE: An Efficient Method for Content-Based Medical Image Retrieval Based on Query Expansion. [PDF]
J Digit Imaging, 2023 Rashad M, Afifi I, Abdelfatah M.
europepmc +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Cloud Information Retrieval: Model Description and Scheme Design
IEEE Access, 2018 The fast development of cloud technology has brought about a new trend in the field of information service: more and more information is being transferred to the cloud as requested.
Zhen Yang, Jiliang Tang, Huan Liu
doaj +1 more source
Knowledge-based Query Expansion in Real-Time Microblog Search
, 2015 Since the length of microblog texts, such as tweets, is strictly limited to 140 characters, traditional Information Retrieval techniques suffer from the vocabulary mismatch problem severely and cannot yield good performance in the context of ...
Fan, Feifan +3 more
core +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
A study of query expansion methods for patent retrieval [PDF]
, 2011 Patent retrieval is a recall-oriented search task where the objective is to find all possible relevant documents. Queries in patent retrieval are typically very long since they take the form of a patent claim or even a full patent application in the ...
Jones, Gareth J.F., Magdy, Walid
core
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source