Results 81 to 90 of about 1,392,110 (286)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Semantic Sequential Query Expansion for Biomedical Article Search

open access: yesIEEE Access, 2018
The conventional sequential dependence model (SDM) has been proved to perform better than the bag of words model for biomedical article search because it pays attention to the sequence information within queries.
Fan Fang, Bo-Wen Zhang, Xu-Cheng Yin
doaj   +1 more source

Document Expansion by Query Prediction

open access: yesCoRR, 2019
One technique to improve the retrieval effectiveness of a search engine is to expand documents with terms that are related or representative of the documents' content.From the perspective of a question answering system, this might comprise questions the document can potentially answer.
Rodrigo Nogueira 0001   +3 more
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

A Taxonomy and Survey of Semantic Approaches for Query Expansion

open access: yesIEEE Access, 2019
Conventional approaches to query expansion (QE) rely on the integration of an unstructured corpus and probabilistic rules for the extraction of candidate expansion terms.
Muhammad Ahsan Raza   +4 more
doaj   +1 more source

Head Concepts Selection for Verbose Medical Queries Expansion

open access: yesIEEE Access, 2020
Semantic concepts and relations encoded in domain-specific ontologies and other medical semantic resources play a crucial role in deciphering terms in medical queries and documents.
Mohammed Maree   +4 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Query expansion for microblog retrieval

open access: yesInternational Journal of Web Science, 2012
The extreme brevity of Microblog posts (such as ‘tweets’) exacerbates the well-known vocabulary mismatch problem when retrieving tweets in response to user queries. In this study, we explore various query expansion approaches as a way to address this problem. We use the Web as a source of query expansion terms.
Ayan Bandyopadhyay   +3 more
openaire   +1 more source

Inter-relaão das técnicas Term Extration e Query Expansion aplicadas na recuperação de documentos textuais [PDF]

open access: yes, 2007
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-graduação em Engenharia e Gestão do ConhecimentoConforme Sighal (2006) as pessoas reconhecem a importância do armazenamento e busca da informação e, com o ...
Bettio, Raphael Winckler de
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

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