Results 101 to 110 of about 1,392,110 (286)

Question-answering, relevance feedback and summarisation : TREC-9 interactive track report [PDF]

open access: yes, 2000
In this paper we report on the effectiveness of query-biased summaries for a question-answering task. Our summarisation system presents searchers with short summaries of documents, composed of a series of highly matching sentences extracted from the ...
Brown, C.   +4 more
core   +5 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

A study of query expansion methods for patent retrieval [PDF]

open access: yes, 2011
Patent retrieval is a recall-oriented search task where the objective is to find all possible relevant documents. Queries in patent retrieval are typically very long since they take the form of a patent claim or even a full patent application in the ...
Magdy, Walid, Jones, Gareth J.F.
core   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Using Windmill Expansion for Document Retrieval

open access: yes, 2009
SEMIOTIKS aims to utilise online information to support the crucial decision–making of those military and civilian agencies involved in the humanitarian removal of landmines in areas of conflict throughout the world.
Liang, Shao   +3 more
core   +1 more source

Named Entity Recognition in Statistical Dataset Search Queries

open access: yesJurnal Nasional Teknik Elektro dan Teknologi Informasi
Search engines must understand user queries to provide relevant search results. Search engines can enhance their understanding of user intent by employing named entity recognition (NER) to identify the entity in the query.
Wildannissa Pinasti   +1 more
doaj   +1 more source

Cloud Information Retrieval: Model Description and Scheme Design

open access: yesIEEE Access, 2018
The fast development of cloud technology has brought about a new trend in the field of information service: more and more information is being transferred to the cloud as requested.
Zhen Yang, Jiliang Tang, Huan Liu
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

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