Results 111 to 120 of about 198,128 (343)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

open access: yesFEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee   +3 more
wiley   +1 more source

An Improved Retrievability-Based Cluster-Resampling Approach for Pseudo Relevance Feedback

open access: yesComputers, 2016
Cluster-based pseudo-relevance feedback (PRF) is an effective approach for searching relevant documents for relevance feedback. Standard approach constructs clusters for PRF only on the basis of high similarity between retrieved documents.
Shariq Bashir
doaj   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Named Entity Recognition in Statistical Dataset Search Queries

open access: yesJurnal Nasional Teknik Elektro dan Teknologi Informasi
Search engines must understand user queries to provide relevant search results. Search engines can enhance their understanding of user intent by employing named entity recognition (NER) to identify the entity in the query.
Wildannissa Pinasti   +1 more
doaj   +1 more source

Privacy-Protected Route-Based Spatial-Textual Location Search in Road Networks

open access: yesIEEE Access, 2019
Location search and recommendation have received significant attention in recent years. To protect the users' privacy, we propose and study a novel privacy-protected route-based spatial-textual location (PPRSTL) query in road networks.
Hongwei Liu   +3 more
doaj   +1 more source

Query Expansion Dengan Menggabungkan Metode Ruang Vektor Dan Wordnet Pada Sistem Information Retrieval [PDF]

open access: yes, 2009
Salah satu metode yang sering digunakan dalam mengukur relevansi dokumen padasistem information retrieval adalah vector space model. Dalam pengembangan metode ini,salah satunya dapat dilakukan dengan cara melakukan perluasan terhadap vektor querynya ...
Nugroho, S. A. (Susetyo)
core  

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

Aggregated Deep Local Features for Remote Sensing Image Retrieval

open access: yesRemote Sensing, 2019
Remote Sensing Image Retrieval remains a challenging topic due to the special nature of Remote Sensing imagery. Such images contain various different semantic objects, which clearly complicates the retrieval task.
Raffaele Imbriaco   +3 more
doaj   +1 more source

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