Results 121 to 130 of about 197,373 (301)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

An Intelligent Feature Concatenation Process-Based Effective Query Expansion for Patent Retrieval Approach Using Optimal Bi-clustering and Enhanced Social Engineering Optimizer

International Journal of Computational Intelligence Systems
The major objective of patent retrieval is to identify relevant documents from a large database. Patent retrieval requests often take the form of patent claims, as in prior art searches, and these searches typically require a long time to complete ...
G. David Raj, Saswati Mukherjee, C. R. Rene Robin, R. L. Jasmine   +3 more
doaj   +1 more source

Asymmetric Feature Maps with Application to Sketch Based Retrieval

, 2017
We propose a novel concept of asymmetric feature maps (AFM), which allows to evaluate multiple kernels between a query and database entries without increasing the memory requirements.
Chum, Ondřej, Tolias, Giorgos
core   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks, Anna Wolska, Diala Ghazal, Dejan Jakimovski, Bianca Weinstock‐Guttman, Alexander Burnham, Niels Bergsland, Michael G. Dwyer, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +10 more
wiley   +1 more source

Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund, Johan Reutfors, Thomas Frisell, Fredrik Piehl   +3 more
wiley   +1 more source

Salton and Buckley’s Landmark Research in Experimental Text Information Retrieval. A Review of: Salton, G., & Buckley, C. (1990). Improving retrieval performance by relevance feedback. Journal of the American Society for Information Science, 41(4), 288–297.

Evidence Based Library and Information Practice, 2011
Objectives – To compare the performance of the vector space model and the probabilistic weighting model of relevance feedback for the overall purpose of determining the most useful relevance feedback procedures.
Christine F. Marton
doaj  

Query Expansion Dengan Menggabungkan Metode Ruang Vektor Dan Wordnet Pada Sistem Information Retrieval [PDF]

, 2009
Salah satu metode yang sering digunakan dalam mengukur relevansi dokumen padasistem information retrieval adalah vector space model. Dalam pengembangan metode ini,salah satunya dapat dilakukan dengan cara melakukan perluasan terhadap vektor querynya ...
Nugroho, S. A. (Susetyo)
core  

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

A Useful Framework for Identification and Analysis of Different Query Expansion Approaches based on the Candidate Expansion Terms Extraction Methods

International Journal of Information Science and Management, 2018
Query expansion is a method for improving retrieval performance by supplementing an original query with additional terms. This process improves the quality of search engine results and helps users to find the required information.
Mohammad Reza Keyvanpour, Zahra Karimi Zandian, Zahra Abdolhosseini   +2 more
doaj