Results 71 to 80 of about 3,764,864 (296)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
MusQ: A Multi-Store Query System for IoT Data Using a Datalog-Like Language
IEEE Access, 2020 The growing number of connected Internet of Things (IoT) devices has increased the necessity for processing IoT data from multiple heterogeneous data stores. IoT data integration is a challenging problem owing to the heterogeneity of data stores in terms
Hani Ramadhan +3 more
doaj +1 more source
Twig Query Optimization Based on Partial Evaluation [PDF]
Jisuanji gongcheng, 2016 TreeMatch algorithm is widely considered to be an effective Twig query algorithm.According to the disadvantage of TreeMatch algorithm’s repeated analysis on Twig pattern,partial evaluation technology in the field of compilation is applied,and a Twig ...
GAO Wanchen,LIAO Husheng,SU Hang
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Implementing GraphQL as a Query Language for Deductive Databases in SWI-Prolog Using DCGs, Quasi Quotations, and Dicts [PDF]
Electronic Proceedings in Theoretical Computer Science, 2017 The methods to access large relational databases in a distributed system are well established: the relational query language SQL often serves as a language for data access and manipulation, and in addition public interfaces are exposed using ...
Falco Nogatz, Dietmar Seipel
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Effective and Efficient Data Access in the Versatile Web Query Language Xcerpt [PDF]
, 2006 Access to Web data has become an integral part of many applications and services. In the past, such data has usually been accessed through human-tailoredHTMLinterfaces.Nowadays, rich client interfaces in desktop applications or, increasingly, in ...
Berger, Sacha +10 more
core +1 more source
NITELIGHT: A Graphical Tool for Semantic Query Construction
, 2008 Query formulation is a key aspect of information retrieval, contributing to both the efficiency and usability of many semantic applications. A number of query languages, such as SPARQL, have been developed for the Semantic Web; however, there are, as yet,
Smart, Paul R. +3 more
core +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source