Results 91 to 100 of about 3,764,864 (296)

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Identification of Design Principles [PDF]

open access: yes, 2004
This report identifies those design principles for a (possibly new) query and transformation language for the Web supporting inference that are considered essential. Based upon these design principles an initial strawman is selected.
Berger, Sacha   +5 more
core   +1 more source

Exploring accumulative query expansion for relevance feedback [PDF]

open access: yes, 2010
For the participation of Dublin City University (DCU) in the Relevance Feedback (RF) track of INEX 2010, we investigated the relation between the length of relevant text passages and the number of RF terms.
Ganguly, Debasis   +5 more
core   +3 more sources

Default logic as a query language

open access: yesIEEE Transactions on Knowledge and Data Engineering, 1994
Research in nonmonotonic reasoning has focused largely on the idea of representing knowledge about the world via rules that are generally true but can be defeated. Even if relational databases are nowadays the main tool for storing very large sets of data, the approach of using nonmonotonic AI formalisms as relational database query languages has been ...
Marco Cadoli   +2 more
openaire   +6 more sources

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Business-oriented customized big data query system and its SQL parser design and implementation

open access: yesMATEC Web of Conferences, 2018
This paper proposes a big data query system for customized queries based on specific business needs. This paper introduces the components and structure of the query system.
Ge Wenshuai, He Gang, Liu Xinwen
doaj   +1 more source

The network query language NOAH

open access: yesProceedings of the 1982 ACM SIGMOD international conference on Management of data - SIGMOD '82, 1982
A non-procedural query language for network databases is described. The language is very powerful as compared to other implemented languages. It allows to formulate complex queries which, among other things, include conditions for CODASYL-sets and conditions for n:m-relationships.
Rieskamp, Michael   +3 more
openaire   +2 more sources

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

open access: yesFEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Exploring sentence level query expansion in language modeling based information retrieval [PDF]

open access: yes, 2010
We introduce two novel methods for query expansion in information retrieval (IR). The basis of these methods is to add the most similar sentences extracted from pseudo-relevant documents to the original query.
Ganguly, Debasis   +2 more
core   +2 more sources

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