Results 111 to 120 of about 3,172,290 (290)
Skyline Preference Query Based on Massive and Incomplete Dataset
Personalized recommendation and the processing of real-time data exemplify the processing of massive data which in the field of Internet-of-Things (IoT) received a great extent of attention in recent literature.
Yan Wang +4 more
doaj +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Retracted: Location-Dependent Query Processing: Semantic Cache for Real-Time Smart City Analytics. [PDF]
And Biomechanics AB.
europepmc +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
An Extensible Query Language for Content Based Image Retrieval [PDF]
One of the most important bits of every search engine is the query interface. Complex interfaces may cause users to struggle in learning the handling. An example is the query language SQL.
Lu, Joan +2 more
core +3 more sources
Graph processing engine based on graph query system
Recently,graph query and graph processing are emphasis of graph-structured data research.However,independent graph system mismatched combining applications,which needed both query and processing.To avoid some issues brought by independent system,such as ...
Xuehan KE, Rong CHEN
doaj
A Unified Approach to Spatial Proximity Query Processing in Dynamic Spatial Networks. [PDF]
Cho HJ.
europepmc +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source

