Results 141 to 150 of about 476,420 (328)

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Processing time-constrained aggregate queries in CASE-DB [PDF]

, 1993
Wen‐Chi Hou, Gültekin Özsoyoğlu
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Intelligent query processing for semantic mediation of information systems

, 2011
Saber Benharzallah, Okba Kazar, Guy Caplat   +2 more
openalex   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Ir-tree query processing in spatial database

, 2016
K Prabhakar, A Devender, G Bhalotia, A Hulgeri, C Nakhe, S Chakrabarti, S Sudarshan, X Cao, L Chen, G Cong, C Jensen, Q Qu, A Skovsgaard, D Wu, M Yiu, S Agrawal, S Chaudhuri, G Das, X Cao, G Cong, C Jensen, X Cao, G Cong, C Jensen, B Ooi, B Chazelle, J Kilian, R Rubinfeld, A Tal, Y.-Y Chen, T Suel, A Markowetz, E Chu, A Baid, X Chai, A Doan, J Naughton, G Cong, C Jensen, D Wu, I Felipe, V Hristidis, N Rishe, V Hristidis, Y Papakonstantinou   +44 more
openalex   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

Processing-in-Memory for Databases: Query Processing and Data Transfer [PDF]

, 2023
Alexander Baumstark, Muhammad Attahir Jibril, Kai-Uwe Sattler   +2 more
openalex   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Service querying to support process variant development

, 2015
N. Chan, Nattawat Nonsung, Walid Gaaloul
openalex   +2 more sources