Results 161 to 170 of about 1,726 (214)

Vascular Disease, Non‐Steroidal Anti‐Inflammatory Drugs and Risk of Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives A history of vascular disease has been shown to be associated with an increased risk of Parkinson's disease, but this may be due to reverse causation. In addition, non‐steroidal anti‐inflammatory drugs are thought to reduce Parkinson's disease risk, but evidence is inconsistent and confounding by prior vascular disease is possible ...
Clare Wotton, Carol Hermon, Sarah Floud, Gillian Reeves, Isobel Barnes   +4 more
wiley   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

Anti‐CD20 Discontinuation Versus Continuation in People Aged Over 50 With Non‐Active Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether discontinuing anti‐CD20 therapy in people with relapsing‐onset MS aged over 50 is associated with an increased risk of relapse, inflammatory activity, confirmed disability accrual, and serious infection compared with continuing therapy.
Alexia Moukhine, Fabien Rollot, Romain Casey, Nicolas Collongues, Sandra Vukusic, Guillaume Mathey, Anne Laure Dubessy, Jonathan Ciron, Jérôme De Seze, Aurélie Ruet, Pierre Labauge, Arnaud Kwiatkowski, Hélène Zephir, Caroline Papeix, Gilles Defer, Christine Lebrun‐Frenay, David Axel Laplaud, Eric Berger, Eric Thouvenot, Jean Pelletier, Abdullatif Al Khedr, Olivier Casez, Bertrand Bourre, Abir Wahab, Laurent Magy, Jean‐Philippe Camdessanché, Ines Doghri, Solène Moulin, Mariana Sarov Rivière, Karolina Hankiewicz, Amélie Dos Santos, Corinne Pottier, Eric Manchon, Jennifer Aboab, Maia Tchikviladze, Thomas David, Gilles Edan, Emmanuelle Le Page, Laure Michel, Anne Kerbrat, OFSEP Investigators   +40 more
wiley   +1 more source

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Distributed query processing

ACM Computing Surveys, 1984
In this paper, various techniques for optimizing queries in distributed databases are presented. Although no attempt is made to cover all proposed algorithms on this topic, quite a few ideas extracted from existing algorithms are outlined. It is hoped that large-scale experiments will be conducted to verify the usefulness of these ideas and that they ...
Clement T. Yu, C. C. Chang
openaire   +2 more sources

Query Processing in PIOS

1995
An approach to query processing in object-oriented stores supporting physical data independence is proposed in this Chapter. In particular, the problem of query optimisation (i e finding efficient execution plans for declarative queries) is investigated. A set of rewrite rules has been defined in order to allow an algebraic optimisation phase.
Rabitti F, Benedetti L, Demi F
openaire   +2 more sources

XML query processing

Proceedings. 20th International Conference on Data Engineering, 2005
XQuery is starting to gain significant traction as a language for querying and transforming XML data. It is used in a variety of different products. Examples to date include XML database systems, XML document repositories, XML data integation, workflow systems, and publish and subscribe systems.
Daniela Florescu, Donald Kossmann
openaire   +1 more source

Query Relaxation in Cooperative Query Processing

2009
This chapter explores new trends of query relaxation strategies that allow to implement a cooperative query processing paradigm. This new paradigm is based on the belief that the user has an idea of what he/she wants and the system has to automatically lead him/her to formulate meaningful queries by relaxing query constraints.
D'Ulizia Arianna, Ferri Fernando, Grifoni Patrizia   +2 more
openaire   +3 more sources

Intermittent query processing

Proceedings of the VLDB Endowment, 2019
Many applications ingest data in an intermittent, yet largely predictable, pattern. Existing systems tend to ignore how data arrives when making decisions about how to update (or refresh) an ongoing query. To address this shortcoming we propose a new query processing paradigm, Intermittent Query Processing (IQP), that bridges query execution and ...
Dixin Tang, Zechao Shang, Aaron J. Elmore, Sanjay Krishnan, Michael J. Franklin   +4 more
openaire   +1 more source

Query Processing in Spatial-Query-by-Sketch

Journal of Visual Languages & Computing, 1997
Abstract Spatial-Query-by-Sketch is the design of a query language for geographic information systems. It allows a user to formulate a spatial query by drawing the desired configuration with a pen on a touch-sensitive computer screen and translates this sketch into a symbolic representation that can be processed against a geographic database.
openaire   +1 more source

Processing Implication on Queries

IEEE Transactions on Software Engineering, 1989
The ability to quickly determine how to derive a given query from a set of prestored fragments is highly demanded in many database applications, especially in distributed database systems, where the communication cost is a major concern. The main difficulty in solving this problem lies in the implication problem given two predicates σQ and σT, can σQ ...
Sun, Xian-he, Kamel, Nabil, Ni, Lionel Ming-Shuan   +2 more
openaire   +2 more sources